Label-free kinetic screening of proteins and virus binding in a 51,200 small-molecule library with a high-throughput ellipsometric scanning microscope

Galina Malovichko, James P. Landry, Andrew P. Proudian, Xiangdong Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using a label-free high-throughput optical scanning microscope we detected endpoints and binding kinetics of RNPC1a, Pyl(1&2) proteins and influenza virus A/PR/8/34 with a library of 51,200 small-molecule compounds from the NCI Developmental Therapeutics Program.

Original languageEnglish (US)
Title of host publicationCLEO: Applications and Technology, CLEO_AT 2013
StatePublished - 2013
EventCLEO: Applications and Technology, CLEO_AT 2013 - San Jose, CA, United States
Duration: Jun 9 2013Jun 14 2013

Other

OtherCLEO: Applications and Technology, CLEO_AT 2013
CountryUnited States
CitySan Jose, CA
Period6/9/136/14/13

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Malovichko, G., Landry, J. P., Proudian, A. P., & Zhu, X. (2013). Label-free kinetic screening of proteins and virus binding in a 51,200 small-molecule library with a high-throughput ellipsometric scanning microscope. In CLEO: Applications and Technology, CLEO_AT 2013