Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism

Rupsa Datta, Christopher Heylman, David Tran, Steven George, Enrico Gratton

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we show mapping of metabolic activity and non-invasive monitoring of drug response of a microphysiological tissue system in a PDMS microfluidic device chamber by fluorescence lifetime imaging of NADH, an endogenous fluorophore.

Original languageEnglish (US)
Title of host publicationLaser Science, LS 2014
PublisherOptical Society of America (OSA)
ISBN (Electronic)1557522863
StatePublished - Jan 1 2014
EventLaser Science, LS 2014 - Tucson, United States
Duration: Oct 19 2014Oct 23 2014

Other

OtherLaser Science, LS 2014
CountryUnited States
CityTucson
Period10/19/1410/23/14

Fingerprint

Fluorophores
Microfluidics
Metabolism
NAD
Labels
Fluorescence
Tissue
Imaging techniques
Monitoring
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Datta, R., Heylman, C., Tran, D., George, S., & Gratton, E. (2014). Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism. In Laser Science, LS 2014 Optical Society of America (OSA).

Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism. / Datta, Rupsa; Heylman, Christopher; Tran, David; George, Steven; Gratton, Enrico.

Laser Science, LS 2014. Optical Society of America (OSA), 2014.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Datta, R, Heylman, C, Tran, D, George, S & Gratton, E 2014, Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism. in Laser Science, LS 2014. Optical Society of America (OSA), Laser Science, LS 2014, Tucson, United States, 10/19/14.
Datta R, Heylman C, Tran D, George S, Gratton E. Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism. In Laser Science, LS 2014. Optical Society of America (OSA). 2014
Datta, Rupsa ; Heylman, Christopher ; Tran, David ; George, Steven ; Gratton, Enrico. / Label - free fluorescence lifetime imaging of microfluidic device based cardiac tissue model metabolism. Laser Science, LS 2014. Optical Society of America (OSA), 2014.
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