We developed an oblique-incidence reflectivity difference (OI-RD) scanning microscope for label-free imaging of microarrays of biomolecules upon solid substrates. We demonstrate that hybridization reactions in an oligonucleotide microarray fabricated upon a glass slide can be detected by such an OI-RD microscope.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Mar 15 2004|
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics