Abstract
Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic techniques that have experienced a tremendous growth in their use in biological and biomedical research. This is, in large part, due to their unique capability of providing label-free intrinsic chemical information of living biological samples at tissue, cellular, or sub-cellular resolutions. This article reviews recent developments in applying these techniques for the characterization of stem cells. A discussion of the potential for these methods to address some of the major challenges in stem cell research is presented, as well as the technological and scientific advancements that are needed to progress the knowledge in the field.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 656-668 |
| Number of pages | 13 |
| Journal | Journal of Biophotonics |
| Volume | 2 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2009 |
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Keywords
- Adult stem cells
- Embryonic stem cells
- Infrared spectroscopy
- Mesenchymal stem cells
- Raman spectroscopy
ASJC Scopus subject areas
- Materials Science(all)
- Engineering(all)
- Physics and Astronomy(all)
- Chemistry(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Label-free biochemical characterization of stem cells using vibrational spectroscopy. / Chan, James W; Lieu, Deborah.
In: Journal of Biophotonics, Vol. 2, No. 11, 11.2009, p. 656-668.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Label-free biochemical characterization of stem cells using vibrational spectroscopy
AU - Chan, James W
AU - Lieu, Deborah
PY - 2009/11
Y1 - 2009/11
N2 - Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic techniques that have experienced a tremendous growth in their use in biological and biomedical research. This is, in large part, due to their unique capability of providing label-free intrinsic chemical information of living biological samples at tissue, cellular, or sub-cellular resolutions. This article reviews recent developments in applying these techniques for the characterization of stem cells. A discussion of the potential for these methods to address some of the major challenges in stem cell research is presented, as well as the technological and scientific advancements that are needed to progress the knowledge in the field.
AB - Raman and infrared (IR) spectroscopy are two complementary vibrational spectroscopic techniques that have experienced a tremendous growth in their use in biological and biomedical research. This is, in large part, due to their unique capability of providing label-free intrinsic chemical information of living biological samples at tissue, cellular, or sub-cellular resolutions. This article reviews recent developments in applying these techniques for the characterization of stem cells. A discussion of the potential for these methods to address some of the major challenges in stem cell research is presented, as well as the technological and scientific advancements that are needed to progress the knowledge in the field.
KW - Adult stem cells
KW - Embryonic stem cells
KW - Infrared spectroscopy
KW - Mesenchymal stem cells
KW - Raman spectroscopy
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UR - http://www.scopus.com/inward/citedby.url?scp=74049084523&partnerID=8YFLogxK
U2 - 10.1002/jbio.200910041
DO - 10.1002/jbio.200910041
M3 - Article
C2 - 19653219
AN - SCOPUS:74049084523
VL - 2
SP - 656
EP - 668
JO - Journal of Biophotonics
JF - Journal of Biophotonics
SN - 1864-063X
IS - 11
ER -