Kv1.1 Takes a deTOR from the Axon to the Dendrite

Eliana Clark; Helene Vacher; James Trimmer

doi:10.1016/j.neuron.2006.10.014

Kv1.1 Takes a deTOR from the Axon to the Dendrite

Eliana Clark, Helene Vacher, James Trimmer

Physiology and Membrane Biology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In the October 6th issue of Science, Raab-Graham et al. described two surprising findings. They discovered that local dendritic translation of Kv1.1 occurs in CA1 dendrites of rat hippocampal slices and in cultured neurons. This local translation is inhibited by NMDA receptor-mediated synaptic signaling acting through the mTOR kinase.

Original language	English (US)
Pages (from-to)	399-401
Number of pages	3
Journal	Neuron
Volume	52
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2006.10.014
State	Published - Nov 9 2006

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.neuron.2006.10.014

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title = "Kv1.1 Takes a deTOR from the Axon to the Dendrite",

abstract = "In the October 6th issue of Science, Raab-Graham et al. described two surprising findings. They discovered that local dendritic translation of Kv1.1 occurs in CA1 dendrites of rat hippocampal slices and in cultured neurons. This local translation is inhibited by NMDA receptor-mediated synaptic signaling acting through the mTOR kinase.",

author = "Eliana Clark and Helene Vacher and James Trimmer",

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AU - Trimmer, James

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AB - In the October 6th issue of Science, Raab-Graham et al. described two surprising findings. They discovered that local dendritic translation of Kv1.1 occurs in CA1 dendrites of rat hippocampal slices and in cultured neurons. This local translation is inhibited by NMDA receptor-mediated synaptic signaling acting through the mTOR kinase.

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Kv1.1 Takes a deTOR from the Axon to the Dendrite

Abstract

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