KV x-ray dual digital tomosynthesis for image guided lung SBRT

Larry Partain, Douglas Boyd, Namho Kim, Andrew Hernandez, Megan E Daly, John M Boone

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Two simulated sets of digital tomosynthesis images of the lungs, each acquired at a 90 degree angle from the other, with 19 projection images used for each set and SART iterative reconstructed, gives dual tomosynthesis slice image quality approaching that of spiral CT, and with a data acquisition time that is 3% of that of cone beam CT. This fast kV acquisition, should allow near real time tracking of lung tumors in patients receiving SBRT, based on a novel TumoTrakTM multi-source X-ray tube design. Until this TumoTrakTM prototype is completed over the next year, its projected performance was simulated from the DRR images created from a spiral CT data set from a lung cancer patient. The resulting dual digital tomosynthesis reconstructed images of the lung tumor were exceptional and approached that of the gold standard Feldkamp CT reconstruction of breath hold, diagnostic, spiral, multirow, CT data. The relative dose at 46 mAs was less than 10% of what it would have been if the digital tomosynthesis had been done at the 472 mAs of the CT data set. This is for a 0.77 fps imaging rate sufficient to resolve respiratory motion in many free breathing patients during SBRT. Such image guidance could decrease the magnitudes of targeting error margins by as much as 20 mm or more in the craniocaudal direction for lower lobe lesions while markedly reducing dose to normal lung, heart and other critical structures. These initial results suggest a wide range of topics for future work.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2016: Physics of Medical Imaging
PublisherSPIE
Volume9783
ISBN (Electronic)9781510600188
DOIs
StatePublished - 2016
EventMedical Imaging 2016: Physics of Medical Imaging - San Diego, United States
Duration: Feb 28 2016Mar 2 2016

Other

OtherMedical Imaging 2016: Physics of Medical Imaging
CountryUnited States
CitySan Diego
Period2/28/163/2/16

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Keywords

  • digital
  • dual
  • image guided
  • kV
  • lung
  • SBRT
  • Tomosynthesis
  • X-ray

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Partain, L., Boyd, D., Kim, N., Hernandez, A., Daly, M. E., & Boone, J. M. (2016). KV x-ray dual digital tomosynthesis for image guided lung SBRT. In Medical Imaging 2016: Physics of Medical Imaging (Vol. 9783). [978361] SPIE. https://doi.org/10.1117/12.2216437