Knoevenagel condensations of β-hemiacetyl esters

Pilho Kim, Marilyn M. Olmstead, Michael H. Nantz, Mark J. Kurth

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


The intermolecular Knoevenagel condensation of β-hemiacetyl ester proceeds by an in situ unmasking of a reactive ω-hydroxy-β-keto ester giving unsaturated ω-hydroxy-β-keto esters 6-12 which accommodate acetal formation. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)4029-4032
Number of pages4
JournalTetrahedron Letters
Issue number21
StatePublished - May 29 2000


  • Acetal formation
  • Eleuthesides
  • Knoevenagel condensation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery


Dive into the research topics of 'Knoevenagel condensations of β-hemiacetyl esters'. Together they form a unique fingerprint.

Cite this