Knoevenagel condensations of β-hemiacetyl esters

Pilho Kim, Marilyn M. Olmstead, Michael H. Nantz, Mark J. Kurth

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The intermolecular Knoevenagel condensation of β-hemiacetyl ester proceeds by an in situ unmasking of a reactive ω-hydroxy-β-keto ester giving unsaturated ω-hydroxy-β-keto esters 6-12 which accommodate acetal formation. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)4029-4032
Number of pages4
JournalTetrahedron Letters
Volume41
Issue number21
StatePublished - May 29 2000

Fingerprint

Condensation
Esters
Acetals

Keywords

  • Acetal formation
  • Eleuthesides
  • Knoevenagel condensation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Kim, P., Olmstead, M. M., Nantz, M. H., & Kurth, M. J. (2000). Knoevenagel condensations of β-hemiacetyl esters. Tetrahedron Letters, 41(21), 4029-4032.

Knoevenagel condensations of β-hemiacetyl esters. / Kim, Pilho; Olmstead, Marilyn M.; Nantz, Michael H.; Kurth, Mark J.

In: Tetrahedron Letters, Vol. 41, No. 21, 29.05.2000, p. 4029-4032.

Research output: Contribution to journalArticle

Kim, P, Olmstead, MM, Nantz, MH & Kurth, MJ 2000, 'Knoevenagel condensations of β-hemiacetyl esters', Tetrahedron Letters, vol. 41, no. 21, pp. 4029-4032.
Kim P, Olmstead MM, Nantz MH, Kurth MJ. Knoevenagel condensations of β-hemiacetyl esters. Tetrahedron Letters. 2000 May 29;41(21):4029-4032.
Kim, Pilho ; Olmstead, Marilyn M. ; Nantz, Michael H. ; Kurth, Mark J. / Knoevenagel condensations of β-hemiacetyl esters. In: Tetrahedron Letters. 2000 ; Vol. 41, No. 21. pp. 4029-4032.
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