Abstract
The intermolecular Knoevenagel condensation of β-hemiacetyl ester proceeds by an in situ unmasking of a reactive ω-hydroxy-β-keto ester giving unsaturated ω-hydroxy-β-keto esters 6-12 which accommodate acetal formation. (C) 2000 Elsevier Science Ltd.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4029-4032 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 41 |
| Issue number | 21 |
| State | Published - May 29 2000 |
Keywords
- Acetal formation
- Eleuthesides
- Knoevenagel condensation
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
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Cite this
Kim, P., Olmstead, M. M., Nantz, M. H., & Kurth, M. J. (2000). Knoevenagel condensations of β-hemiacetyl esters. Tetrahedron Letters, 41(21), 4029-4032.