Klinefelter's syndrome and precocious puberty: a harbinger for tumor.

Eric A Kurzrock; Hari Siva Gurunadha Rao Tunuguntla; Joseph E. Busby; Regina F Gandour-Edwards; Laurence A. Goldman

Klinefelter's syndrome and precocious puberty: a harbinger for tumor.

Eric A Kurzrock, Hari Siva Gurunadha Rao Tunuguntla, Joseph E. Busby, Regina F Gandour-Edwards, Laurence A. Goldman

Research output: Contribution to journal › Article › peer-review

Abstract

Boys with Klinefelter's syndrome are at an increased risk of precocious puberty. Most cases are either idiopathic or due to a mediastinal tumor. Patients with Klinefelter's syndrome are at a high risk of primary, extragonadal germ cell tumors, which are usually nonseminomatous, but can be a mixed type with seminomatous elements. The differential diagnosis of precocious puberty includes mediastinal tumors, especially in boys with Klinefelter's syndrome.

Original language	English (US)
Pages (from-to)	514
Number of pages	1
Journal	Urology
Volume	60
Issue number	3
State	Published - Sep 2002

ASJC Scopus subject areas

Urology

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abstract = "Boys with Klinefelter's syndrome are at an increased risk of precocious puberty. Most cases are either idiopathic or due to a mediastinal tumor. Patients with Klinefelter's syndrome are at a high risk of primary, extragonadal germ cell tumors, which are usually nonseminomatous, but can be a mixed type with seminomatous elements. The differential diagnosis of precocious puberty includes mediastinal tumors, especially in boys with Klinefelter's syndrome.",

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AU - Kurzrock, Eric A

AU - Tunuguntla, Hari Siva Gurunadha Rao

AU - Busby, Joseph E.

AU - Gandour-Edwards, Regina F

AU - Goldman, Laurence A.

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AB - Boys with Klinefelter's syndrome are at an increased risk of precocious puberty. Most cases are either idiopathic or due to a mediastinal tumor. Patients with Klinefelter's syndrome are at a high risk of primary, extragonadal germ cell tumors, which are usually nonseminomatous, but can be a mixed type with seminomatous elements. The differential diagnosis of precocious puberty includes mediastinal tumors, especially in boys with Klinefelter's syndrome.

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