Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. The role of various members of the kinesin superfamily in chromosome segregation and spindle morphogenesis was described in TCB last year in parts of a series on cytoplasmic motor proteins* * The kinesin superfamily: tails of functional redundancy by Lawrence S. B. Goldstein [TCB 1, 93-98 (1991)]; Motor proteins in cell division by Kenneth E. Sawin and Jonathan M. Scholey [TCB 1, 122-129 (1991)].. In this brief update, Helen Epstein and Jon Scholey comment on new findings that have improved our understanding of the functions of kinesin-related proteins in mitosis and meiosis.
ASJC Scopus subject areas
- Cell Biology