Kidney microvasculature in health and disease

Kuang-Yu Jen, Lukas Haragsim, Zoltan G. Laszik

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

The renal microvasculature is composed of the glomerular and peritubular capillary beds which supply the cellular constituents of the kidney with oxygen and nutrients as well as maintain renal function by providing an adequate glomerular filtration rate. As a result, endothelial dysfunction within the kidney can lead to devastating consequences. Recently, a plethora of information regarding the molecular players involved in kidney microvasculature development and disease has emerged. Many of these studies focus on intricate signaling pathways within the local microenvironment of endothelial cells. Here, we highlight some of these studies and relate them to the molecular pathogenesis of glomerular and peritubular endothelial cells in both native and transplant renal diseases.

Original languageEnglish (US)
Title of host publicationExperimental Models for Renal Diseases
Subtitle of host publicationPathogenesis and Diagnosis
PublisherS. Karger AG
Pages51-72
Number of pages22
Volume169
ISBN (Electronic)9783805595384
ISBN (Print)9783805595377
DOIs
StatePublished - Jan 14 2011
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Jen, K-Y., Haragsim, L., & Laszik, Z. G. (2011). Kidney microvasculature in health and disease. In Experimental Models for Renal Diseases: Pathogenesis and Diagnosis (Vol. 169, pp. 51-72). S. Karger AG. https://doi.org/10.1159/000313945