Keratinization and necrosis: Morphologic aspects of lymphatic metastases in ultrasound

Jürgen Mäurer, Carston Willam, Herrmann J. Steinkamp, Friedrich D Knollmann, Roland Felix

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

RATIONALE AND OBJECTIVES. The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sohographic appearance. In addition to criteria such as the longitudinal/transversal quotient, sonomorphology could support a more precise differential diagnosis of neck lymph nodes. METHODS. In 105 of 145 patients with histologically proved head and neck carcinomas, 187 lymph node metastases were detected by ultrasound. Sohomorphology was compared with the corresponding histology. RESULTS. Five sohomorphologic groups could be differentiated. (1) Thirty-one percent of the metastases were homogenous. (2) Concerning the more complex morphology of lymph node metastases in ultrasound, echolucent forms could be differentiated from echogenie textures: low- or nondifferentiated and nonkeratinizing metastases appeared echolucent and cyst-like, with dorsal signal amplification. (3) Nonkeratinizing lymphomas with necrosis showed single or multiple echolucent intranodal lesions. (4) In correlation with an increasing keratinization, the echogenecity of the lymph nodes increased and intranodal echogenie inclusions appeared. (5) An extended keratinization correlated with a central echogenecity. CONCLUSIONS. The morphologic assessment of lymph nodes in ultrasound allows for primary histologic and prognostic evaluation of lymph node metastases.

Original languageEnglish (US)
Pages (from-to)545-549
Number of pages5
JournalInvestigative Radiology
Volume31
Issue number9
DOIs
StatePublished - Sep 1996
Externally publishedYes

Fingerprint

Lymphatic Metastasis
Necrosis
Lymph Nodes
Neoplasm Metastasis
Neck
Cysts
Lymphoma
Histology
Differential Diagnosis
Retrospective Studies
Head
Carcinoma

Keywords

  • echomorphology
  • keratinization
  • Lymph node metastasis
  • necrosis
  • ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Keratinization and necrosis : Morphologic aspects of lymphatic metastases in ultrasound. / Mäurer, Jürgen; Willam, Carston; Steinkamp, Herrmann J.; Knollmann, Friedrich D; Felix, Roland.

In: Investigative Radiology, Vol. 31, No. 9, 09.1996, p. 545-549.

Research output: Contribution to journalArticle

Mäurer, Jürgen ; Willam, Carston ; Steinkamp, Herrmann J. ; Knollmann, Friedrich D ; Felix, Roland. / Keratinization and necrosis : Morphologic aspects of lymphatic metastases in ultrasound. In: Investigative Radiology. 1996 ; Vol. 31, No. 9. pp. 545-549.
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