Issues in conducting a cancer risk assessment using epidemiologic data: Arsenic as a case study

Irva Hertz-Picciotto, D. A. Holtzman

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Using human data to extrapolate cancer risks at ambient levels of airborne pollutants avoids the uncertainty due to interspecies differences, but introduces other uncertainties. The unusually extensive data relating lung cancer to occupational inhalation of arsenic provide examples of 3 uncertainties: the extrapolation from partial to full lifetime risks, from high to low doses, and between populations with differing smoking habits.

Original languageEnglish (US)
Pages (from-to)219-223
Number of pages5
JournalExperimental Pathology
Volume37
Issue number1-4
StatePublished - 1989
Externally publishedYes

Keywords

  • airborne pollutants, cancer risk
  • arsenic
  • cancer risk, assessment
  • lung cancer
  • smoking habits

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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