Abstract
To test nonshivering thermogenic (NST) capacity of lean and obese Zucker rats, 4 doses of isoproterenol, ranging in concentration from 0.25 to 6.0 μg/min·kg.75, were intravenously infused into 16 to 18 week old male rats, and oxygen consumption was continously monitored. Obese rats had a decreased NST response relative to lean littermates. This lowered thermogenic response of the obese rats cannot be attributed to a decreased mass of brown adipose tissue since both the cervical and interscapular depots from obese rats weighed significantly more than did those from lean rats.
Original language | English (US) |
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Pages (from-to) | 627-630 |
Number of pages | 4 |
Journal | Pharmacology, Biochemistry and Behavior |
Volume | 16 |
Issue number | 4 |
DOIs | |
State | Published - 1982 |
ASJC Scopus subject areas
- Biochemistry
- Behavioral Neuroscience
- Pharmacology