Abstract
A highly T-lymphotropic virus was isolated from cats in a cattery in which all the animals were seronegative for feline leukemia virus. A number of cats in one pen had died and several had an immunodeficiency-like syndrome. Only 1 of 18 normal cats in the cattery showed serologic evidence of infection with this new virus, whereas 10 of 25 cats with signs of ill health were seropositive for the virus. Tentatively designated feline T-lymphotropic lentivirus, this new feline retrovirus appears to be antigenically distinct from human immunodeficiency virus. There is no evidence for cat-to-human transmission of the agent. Kittens experimentally infected by way of blood or plasma from naturally infected animals developed generalized lymphadenopathy several weeks later, became transiently febrile and leukopenic, and continued to show a generalized lymphadenopathy 5 months after infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 790-793 |
| Number of pages | 4 |
| Journal | Science |
| Volume | 235 |
| Issue number | 4790 |
| State | Published - 1987 |
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Cite this
Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome. / Pedersen, Niels C; Ho, E. W.; Brown, M. L.; Yamamoto, J. K.
In: Science, Vol. 235, No. 4790, 1987, p. 790-793.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome
AU - Pedersen, Niels C
AU - Ho, E. W.
AU - Brown, M. L.
AU - Yamamoto, J. K.
PY - 1987
Y1 - 1987
N2 - A highly T-lymphotropic virus was isolated from cats in a cattery in which all the animals were seronegative for feline leukemia virus. A number of cats in one pen had died and several had an immunodeficiency-like syndrome. Only 1 of 18 normal cats in the cattery showed serologic evidence of infection with this new virus, whereas 10 of 25 cats with signs of ill health were seropositive for the virus. Tentatively designated feline T-lymphotropic lentivirus, this new feline retrovirus appears to be antigenically distinct from human immunodeficiency virus. There is no evidence for cat-to-human transmission of the agent. Kittens experimentally infected by way of blood or plasma from naturally infected animals developed generalized lymphadenopathy several weeks later, became transiently febrile and leukopenic, and continued to show a generalized lymphadenopathy 5 months after infection.
AB - A highly T-lymphotropic virus was isolated from cats in a cattery in which all the animals were seronegative for feline leukemia virus. A number of cats in one pen had died and several had an immunodeficiency-like syndrome. Only 1 of 18 normal cats in the cattery showed serologic evidence of infection with this new virus, whereas 10 of 25 cats with signs of ill health were seropositive for the virus. Tentatively designated feline T-lymphotropic lentivirus, this new feline retrovirus appears to be antigenically distinct from human immunodeficiency virus. There is no evidence for cat-to-human transmission of the agent. Kittens experimentally infected by way of blood or plasma from naturally infected animals developed generalized lymphadenopathy several weeks later, became transiently febrile and leukopenic, and continued to show a generalized lymphadenopathy 5 months after infection.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023137671&partnerID=8YFLogxK
M3 - Article
C2 - 3643650
AN - SCOPUS:0023137671
VL - 235
SP - 790
EP - 793
JO - Science
JF - Science
SN - 0036-8075
IS - 4790
ER -