Abstract
Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.
Original language | English (US) |
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Article number | e02232-18 |
Journal | Antimicrobial Agents and Chemotherapy |
DOIs | |
State | Published - Mar 1 2019 |
Keywords
- Coccidioides
- Isavuconazole
- Meningitis
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases