Isavuconazole in the treatment of coccidioidal meningitis

Arash Heidari, Miriam Quinlan, David J. Benjamin, Brett Laurence, Anandit Mu, Tiffany Ngai, Wes J. Hoffman, Stuart H Cohen, Ian Howard Mchardy, Royce Johnson, George Richard Thompson

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.

Original languageEnglish (US)
Article numbere02232-18
JournalAntimicrobial Agents and Chemotherapy
StatePublished - Mar 1 2019


  • Coccidioides
  • Isavuconazole
  • Meningitis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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