Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study

Juliana V. Baldo, Silvia A. Bunge, Stephen M. Wilson, Nina Dronkers

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Previous studies with brain-injured patients have suggested that language abilities are necessary for complex problem-solving, even when tasks are non-verbal. In the current study, we tested this notion by analyzing behavioral and neuroimaging data from a large group of left-hemisphere stroke patients (n=107) suffering from a range of language impairment from none to severe. Patients were tested on the Raven's Colored Progressive Matrices (RCPM), a non-verbal test of reasoning that requires participants to complete a visual pattern or sequence with one of six possible choices. For some items, the solution could be determined by visual pattern-matching, but other items required more complex, relational reasoning. As predicted, performance on the relational-reasoning items was disproportionately affected in language-impaired patients with aphasia, relative to non-aphasic, left-hemisphere patients. A voxel-based lesion symptom mapping (VLSM) procedure was used to relate patients' RCPM performance with areas of damage in the brain. Results showed that deficits on the relational reasoning problems were associated with lesions in the left middle and superior temporal gyri, regions essential for language processing, as well as in the left inferior parietal lobule. In contrast, the visual pattern-matching condition was associated with lesions in posterior portions of the left hemisphere that subserve visual processing, namely, occipital and inferotemporal cortex. These findings provide compelling support for the idea that language is critical for higher-level reasoning and problem-solving.

Original languageEnglish (US)
Pages (from-to)59-64
Number of pages6
JournalBrain and Language
Volume113
Issue number2
DOIs
StatePublished - May 2010

Fingerprint

Language
language
Crows
Temporal Lobe
brain
speech disorder
Occipital Lobe
stroke
Parietal Lobe
Aptitude
Aphasia
Brain
performance
deficit
Neuroimaging
damages
Lesion
Stroke
ability
Group

Keywords

  • Aphasia
  • Executive functioning
  • Language
  • Lesion mapping
  • Problem-solving
  • Reasoning
  • Temporal lobe

ASJC Scopus subject areas

  • Linguistics and Language
  • Speech and Hearing
  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience

Cite this

Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study. / Baldo, Juliana V.; Bunge, Silvia A.; Wilson, Stephen M.; Dronkers, Nina.

In: Brain and Language, Vol. 113, No. 2, 05.2010, p. 59-64.

Research output: Contribution to journalArticle

Baldo, Juliana V. ; Bunge, Silvia A. ; Wilson, Stephen M. ; Dronkers, Nina. / Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study. In: Brain and Language. 2010 ; Vol. 113, No. 2. pp. 59-64.
@article{8e7c3de0c7f14cdbb0b9ddd3f55d2050,
title = "Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study",
abstract = "Previous studies with brain-injured patients have suggested that language abilities are necessary for complex problem-solving, even when tasks are non-verbal. In the current study, we tested this notion by analyzing behavioral and neuroimaging data from a large group of left-hemisphere stroke patients (n=107) suffering from a range of language impairment from none to severe. Patients were tested on the Raven's Colored Progressive Matrices (RCPM), a non-verbal test of reasoning that requires participants to complete a visual pattern or sequence with one of six possible choices. For some items, the solution could be determined by visual pattern-matching, but other items required more complex, relational reasoning. As predicted, performance on the relational-reasoning items was disproportionately affected in language-impaired patients with aphasia, relative to non-aphasic, left-hemisphere patients. A voxel-based lesion symptom mapping (VLSM) procedure was used to relate patients' RCPM performance with areas of damage in the brain. Results showed that deficits on the relational reasoning problems were associated with lesions in the left middle and superior temporal gyri, regions essential for language processing, as well as in the left inferior parietal lobule. In contrast, the visual pattern-matching condition was associated with lesions in posterior portions of the left hemisphere that subserve visual processing, namely, occipital and inferotemporal cortex. These findings provide compelling support for the idea that language is critical for higher-level reasoning and problem-solving.",
keywords = "Aphasia, Executive functioning, Language, Lesion mapping, Problem-solving, Reasoning, Temporal lobe",
author = "Baldo, {Juliana V.} and Bunge, {Silvia A.} and Wilson, {Stephen M.} and Nina Dronkers",
year = "2010",
month = "5",
doi = "10.1016/j.bandl.2010.01.004",
language = "English (US)",
volume = "113",
pages = "59--64",
journal = "Brain and Language",
issn = "0093-934X",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study

AU - Baldo, Juliana V.

AU - Bunge, Silvia A.

AU - Wilson, Stephen M.

AU - Dronkers, Nina

PY - 2010/5

Y1 - 2010/5

N2 - Previous studies with brain-injured patients have suggested that language abilities are necessary for complex problem-solving, even when tasks are non-verbal. In the current study, we tested this notion by analyzing behavioral and neuroimaging data from a large group of left-hemisphere stroke patients (n=107) suffering from a range of language impairment from none to severe. Patients were tested on the Raven's Colored Progressive Matrices (RCPM), a non-verbal test of reasoning that requires participants to complete a visual pattern or sequence with one of six possible choices. For some items, the solution could be determined by visual pattern-matching, but other items required more complex, relational reasoning. As predicted, performance on the relational-reasoning items was disproportionately affected in language-impaired patients with aphasia, relative to non-aphasic, left-hemisphere patients. A voxel-based lesion symptom mapping (VLSM) procedure was used to relate patients' RCPM performance with areas of damage in the brain. Results showed that deficits on the relational reasoning problems were associated with lesions in the left middle and superior temporal gyri, regions essential for language processing, as well as in the left inferior parietal lobule. In contrast, the visual pattern-matching condition was associated with lesions in posterior portions of the left hemisphere that subserve visual processing, namely, occipital and inferotemporal cortex. These findings provide compelling support for the idea that language is critical for higher-level reasoning and problem-solving.

AB - Previous studies with brain-injured patients have suggested that language abilities are necessary for complex problem-solving, even when tasks are non-verbal. In the current study, we tested this notion by analyzing behavioral and neuroimaging data from a large group of left-hemisphere stroke patients (n=107) suffering from a range of language impairment from none to severe. Patients were tested on the Raven's Colored Progressive Matrices (RCPM), a non-verbal test of reasoning that requires participants to complete a visual pattern or sequence with one of six possible choices. For some items, the solution could be determined by visual pattern-matching, but other items required more complex, relational reasoning. As predicted, performance on the relational-reasoning items was disproportionately affected in language-impaired patients with aphasia, relative to non-aphasic, left-hemisphere patients. A voxel-based lesion symptom mapping (VLSM) procedure was used to relate patients' RCPM performance with areas of damage in the brain. Results showed that deficits on the relational reasoning problems were associated with lesions in the left middle and superior temporal gyri, regions essential for language processing, as well as in the left inferior parietal lobule. In contrast, the visual pattern-matching condition was associated with lesions in posterior portions of the left hemisphere that subserve visual processing, namely, occipital and inferotemporal cortex. These findings provide compelling support for the idea that language is critical for higher-level reasoning and problem-solving.

KW - Aphasia

KW - Executive functioning

KW - Language

KW - Lesion mapping

KW - Problem-solving

KW - Reasoning

KW - Temporal lobe

UR - http://www.scopus.com/inward/record.url?scp=77951499449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951499449&partnerID=8YFLogxK

U2 - 10.1016/j.bandl.2010.01.004

DO - 10.1016/j.bandl.2010.01.004

M3 - Article

VL - 113

SP - 59

EP - 64

JO - Brain and Language

JF - Brain and Language

SN - 0093-934X

IS - 2

ER -