Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?

Larry D Cowgill, David J. Polzin, Jonathan Elliott, Mary B. Nabity, Gilad Segev, Gregory F. Grauer, Scott Brown, Cathy Langston, Astrid M. van Dongen

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

International Renal Interest Society chronic kidney disease Stage 1 and acute kidney injury Grade I categorizations of kidney disease are often confused or ignored because patients are nonazotemic and generally asymptomatic. Recent evidence suggests these seemingly disparate conditions may be mechanistically linked and interrelated. Active kidney injury biomarkers have the potential to establish a new understanding for traditional views of chronic kidney disease, including its early identification and possible mediators of its progression, which, if validated, would establish a new and sophisticated paradigm for the understanding and approach to the diagnostic evaluation, and treatment of urinary disease in dogs and cats.

Original languageEnglish (US)
Pages (from-to)995-1013
Number of pages19
JournalVeterinary Clinics of North America - Small Animal Practice
Volume46
Issue number6
DOIs
StatePublished - Nov 1 2016

Fingerprint

kidney diseases
Chronic Renal Insufficiency
Acute Kidney Injury
Cat Diseases
kidneys
Dog Diseases
Kidney
Kidney Diseases
cat diseases
dog diseases
Biomarkers
biomarkers
Wounds and Injuries
Therapeutics

Keywords

  • IRIS AKI grade I
  • IRIS CKD stage 1
  • Kidney biomarkers
  • Progressive chronic kidney disease

ASJC Scopus subject areas

  • Small Animals

Cite this

Cowgill, L. D., Polzin, D. J., Elliott, J., Nabity, M. B., Segev, G., Grauer, G. F., ... van Dongen, A. M. (2016). Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury? Veterinary Clinics of North America - Small Animal Practice, 46(6), 995-1013. https://doi.org/10.1016/j.cvsm.2016.06.001

Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury? / Cowgill, Larry D; Polzin, David J.; Elliott, Jonathan; Nabity, Mary B.; Segev, Gilad; Grauer, Gregory F.; Brown, Scott; Langston, Cathy; van Dongen, Astrid M.

In: Veterinary Clinics of North America - Small Animal Practice, Vol. 46, No. 6, 01.11.2016, p. 995-1013.

Research output: Contribution to journalReview article

Cowgill, LD, Polzin, DJ, Elliott, J, Nabity, MB, Segev, G, Grauer, GF, Brown, S, Langston, C & van Dongen, AM 2016, 'Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?', Veterinary Clinics of North America - Small Animal Practice, vol. 46, no. 6, pp. 995-1013. https://doi.org/10.1016/j.cvsm.2016.06.001
Cowgill, Larry D ; Polzin, David J. ; Elliott, Jonathan ; Nabity, Mary B. ; Segev, Gilad ; Grauer, Gregory F. ; Brown, Scott ; Langston, Cathy ; van Dongen, Astrid M. / Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?. In: Veterinary Clinics of North America - Small Animal Practice. 2016 ; Vol. 46, No. 6. pp. 995-1013.
@article{cad3925244014defa56bb6cf7b2586bf,
title = "Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?",
abstract = "International Renal Interest Society chronic kidney disease Stage 1 and acute kidney injury Grade I categorizations of kidney disease are often confused or ignored because patients are nonazotemic and generally asymptomatic. Recent evidence suggests these seemingly disparate conditions may be mechanistically linked and interrelated. Active kidney injury biomarkers have the potential to establish a new understanding for traditional views of chronic kidney disease, including its early identification and possible mediators of its progression, which, if validated, would establish a new and sophisticated paradigm for the understanding and approach to the diagnostic evaluation, and treatment of urinary disease in dogs and cats.",
keywords = "IRIS AKI grade I, IRIS CKD stage 1, Kidney biomarkers, Progressive chronic kidney disease",
author = "Cowgill, {Larry D} and Polzin, {David J.} and Jonathan Elliott and Nabity, {Mary B.} and Gilad Segev and Grauer, {Gregory F.} and Scott Brown and Cathy Langston and {van Dongen}, {Astrid M.}",
year = "2016",
month = "11",
day = "1",
doi = "10.1016/j.cvsm.2016.06.001",
language = "English (US)",
volume = "46",
pages = "995--1013",
journal = "Veterinary Clinics of North America - Small Animal Practice",
issn = "0195-5616",
publisher = "W.B. Saunders Ltd",
number = "6",

}

TY - JOUR

T1 - Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?

AU - Cowgill, Larry D

AU - Polzin, David J.

AU - Elliott, Jonathan

AU - Nabity, Mary B.

AU - Segev, Gilad

AU - Grauer, Gregory F.

AU - Brown, Scott

AU - Langston, Cathy

AU - van Dongen, Astrid M.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - International Renal Interest Society chronic kidney disease Stage 1 and acute kidney injury Grade I categorizations of kidney disease are often confused or ignored because patients are nonazotemic and generally asymptomatic. Recent evidence suggests these seemingly disparate conditions may be mechanistically linked and interrelated. Active kidney injury biomarkers have the potential to establish a new understanding for traditional views of chronic kidney disease, including its early identification and possible mediators of its progression, which, if validated, would establish a new and sophisticated paradigm for the understanding and approach to the diagnostic evaluation, and treatment of urinary disease in dogs and cats.

AB - International Renal Interest Society chronic kidney disease Stage 1 and acute kidney injury Grade I categorizations of kidney disease are often confused or ignored because patients are nonazotemic and generally asymptomatic. Recent evidence suggests these seemingly disparate conditions may be mechanistically linked and interrelated. Active kidney injury biomarkers have the potential to establish a new understanding for traditional views of chronic kidney disease, including its early identification and possible mediators of its progression, which, if validated, would establish a new and sophisticated paradigm for the understanding and approach to the diagnostic evaluation, and treatment of urinary disease in dogs and cats.

KW - IRIS AKI grade I

KW - IRIS CKD stage 1

KW - Kidney biomarkers

KW - Progressive chronic kidney disease

UR - http://www.scopus.com/inward/record.url?scp=84996602522&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84996602522&partnerID=8YFLogxK

U2 - 10.1016/j.cvsm.2016.06.001

DO - 10.1016/j.cvsm.2016.06.001

M3 - Review article

VL - 46

SP - 995

EP - 1013

JO - Veterinary Clinics of North America - Small Animal Practice

JF - Veterinary Clinics of North America - Small Animal Practice

SN - 0195-5616

IS - 6

ER -