Is Bicarbonate Therapy Useful?

Katrina Hopper

Research output: Contribution to journal › Review article

1 Citation (Scopus)

Abstract

Despite concerns about the negative effects of metabolic acidosis, there is minimal evidence that sodium bicarbonate administration is an effective treatment. In addition, sodium bicarbonate therapy is associated with many adverse effects, including paradoxic intracellular acidosis, hypokalemia, hypocalcemia, hypernatremia, and hyperosmolality. Definitive recommendations regarding bicarbonate therapy are challenging as there is little high-quality evidence available. In most clinical scenarios of metabolic acidosis, treatment efforts should focus on resolution of the underlying cause, and sodium bicarbonate therapy should be used with caution, if at all. An exception to this is kidney disease, wherein sodium bicarbonate therapy may have a valuable role.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalVeterinary Clinics of North America - Small Animal Practice
Volume47
Issue number2
DOIs
StatePublished - Mar 1 2017

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Sodium Bicarbonate
sodium bicarbonate
Bicarbonates
bicarbonates
acidosis
Acidosis
therapeutics
Hypernatremia
hypokalemia
hypocalcemia
Hypokalemia
Hypocalcemia
Kidney Diseases
Therapeutics
kidney diseases
adverse effects

Keywords

  • Diabetic ketoacidosis
  • Ionized calcium
  • Kidney disease
  • Lactic acidosis
  • Metabolic acidosis
  • Potassium

ASJC Scopus subject areas

  • Small Animals

Cite this

Is Bicarbonate Therapy Useful? / Hopper, Katrina.

In: Veterinary Clinics of North America - Small Animal Practice, Vol. 47, No. 2, 01.03.2017, p. 343-349.

Research output: Contribution to journal › Review article

Hopper, K 2017, 'Is Bicarbonate Therapy Useful?', Veterinary Clinics of North America - Small Animal Practice, vol. 47, no. 2, pp. 343-349. https://doi.org/10.1016/j.cvsm.2016.09.005
Hopper K. Is Bicarbonate Therapy Useful? Veterinary Clinics of North America - Small Animal Practice. 2017 Mar 1;47(2):343-349. https://doi.org/10.1016/j.cvsm.2016.09.005
Hopper, Katrina. / Is Bicarbonate Therapy Useful?. In: Veterinary Clinics of North America - Small Animal Practice. 2017 ; Vol. 47, No. 2. pp. 343-349.
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