Is Bicarbonate Therapy Useful?

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Despite concerns about the negative effects of metabolic acidosis, there is minimal evidence that sodium bicarbonate administration is an effective treatment. In addition, sodium bicarbonate therapy is associated with many adverse effects, including paradoxic intracellular acidosis, hypokalemia, hypocalcemia, hypernatremia, and hyperosmolality. Definitive recommendations regarding bicarbonate therapy are challenging as there is little high-quality evidence available. In most clinical scenarios of metabolic acidosis, treatment efforts should focus on resolution of the underlying cause, and sodium bicarbonate therapy should be used with caution, if at all. An exception to this is kidney disease, wherein sodium bicarbonate therapy may have a valuable role.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalVeterinary Clinics of North America - Small Animal Practice
Volume47
Issue number2
DOIs
StatePublished - Mar 1 2017

Keywords

  • Diabetic ketoacidosis
  • Ionized calcium
  • Kidney disease
  • Lactic acidosis
  • Metabolic acidosis
  • Potassium

ASJC Scopus subject areas

  • Small Animals

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