IRIDIUM‐192 INTERSTITIAL BRACHYTHERAPY OF EQUINE SARCOID

Jane M. Turrel, Susan M Stover, Joy Gyorgyfalvy

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Twenty‐three equine sarcoids in 22 horses were treated, using an afterloading technique, with iridium‐192 (192Ir) interstitial radiation therapy. Previously unsuccessful treatment in 14 horses included surgical excision, cryosurgery, hyperthermia, and nonspecific immunotherapy. Twenty tumors were located in the skin of the head, and three were in the skin of the extremities. Before implantation, surgical debulking was done in six tumors, and hyperthermia (43°C, 30 min) was done in three tumors. Total implantation time varied from 4 to 14 days to give radiation doses of 52–93 Gy. The criteria for assessment of therapy were tumor response, tumor‐free incidence at one year, and complications. Follow‐up times ranged from six to 41 months (mean, 20 months). All tumors of the head and two tumors of the extremities had complete response to therapy. One sarcoid of the extremity had partial response to treatment. Tumor recurence was seen in the head of one horse. Of 16 horses followed for one year, the tumor‐free incidence was 94% (15/16). Complications were severe local necrosis in two horses and deep infection in one horse. It was concluded that 192Ir interstitial brachytherapy was an effective treatment of recurrent and difficult‐to‐manage equine sarcoid.

Original languageEnglish (US)
Pages (from-to)20-24
Number of pages5
JournalVeterinary Radiology
Volume26
Issue number1
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

sarcoid
Brachytherapy
Horses
neoplasms
horses
Neoplasms
Extremities
Head
fever
Fever
cryosurgery
incidence
therapeutics
excision
Therapeutics
immunotherapy
Skin
Cryosurgery
radiotherapy
Incidence

Keywords

  • equine sarcoid
  • interstitial brachytherapy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

IRIDIUM‐192 INTERSTITIAL BRACHYTHERAPY OF EQUINE SARCOID. / Turrel, Jane M.; Stover, Susan M; Gyorgyfalvy, Joy.

In: Veterinary Radiology, Vol. 26, No. 1, 1985, p. 20-24.

Research output: Contribution to journalArticle

Turrel, Jane M. ; Stover, Susan M ; Gyorgyfalvy, Joy. / IRIDIUM‐192 INTERSTITIAL BRACHYTHERAPY OF EQUINE SARCOID. In: Veterinary Radiology. 1985 ; Vol. 26, No. 1. pp. 20-24.
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