Investigation of three newly identified equine parvoviruses in blood and nasal fluid samples of clinically healthy horses and horses with acute onset of respiratory disease

Nicola Pusterla, Kaitlyn James, Samantha Barnum, Eric Delwart

Research output: Contribution to journalArticlepeer-review

Abstract

Three newly identified equine parvoviruses (equine parvovirus hepatitis (EqPV‐H), equine parvovirus CSF (EqPV‐CSF) and equine copivirus (Eqcopivirus)) have recently been discov-ered in horses with respiratory signs. However, the clinical impact of these three equine parvovi-ruses has yet to be determined. Nasal fluid samples and blood from 667 equids with acute onset of fever and respiratory signs submitted to a diagnostic laboratory were analyzed for the presence of common equine respiratory pathogens (equine influenza virus, equine herpesvirus‐1/‐4, equine rhi-nitis A and B virus, S. equi subspecies equi) as well as EqPV‐H, EqPV‐CSF and Eqcopivirus by qPCR. An additional 87 clinically healthy horses served as controls. One hundred and seventeen sick horses tested qPCR‐positive for at least one of the three parvoviruses. Co‐infections with common respiratory pathogens and parvoviruses were seen in 39 sick equids. All 87 clinically healthy horses tested qPCR‐negative for all tested common respiratory pathogens and 10 healthy horses tested qPCR‐positive for one of the equine parvoviruses. When the frequency of detection for EqPV‐H, EqPV‐CSF and Eqcopivirus of equids with respiratory signs was compared to that of clinically healthy horses, the difference was not statistically significant (p > 0.05), suggesting that the three recently identified equine parvoviruses do not contribute to the clinical picture of equids with respiratory disease.

Original languageEnglish (US)
Article number3006
JournalAnimals
Volume11
Issue number10
DOIs
StatePublished - Oct 2021

Keywords

  • Blood
  • Equine copivirus
  • Equine parvovirus CSF
  • Equine parvovirus hepatitis
  • Equine parvoviruses
  • Healthy horses
  • Nasal fluid
  • QPCR
  • Sick equids

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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