Investigation of Anaplasma marginale seroprevalence in a traditionally managed large California beef herd

Thomas R. Tucker, Sharif S Aly, John Maas, Josh S. Davy, Janet E Foley

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Recent observations by stakeholders suggested that ecosystem changes may be driving an increased incidence of bovine erythrocytic anaplasmosis, resulting in a reemerging cattle disease in California. The objective of this prospective cohort study was to estimate the incidence of Anaplasma marginale infection using seroconversion in a northern California beef cattle herd. A total of 143 Black Angus cattle (106 prebreeding heifers and 37 cows) were enrolled in the study. Serum samples were collected to determine Anaplasma marginale seroprevalence using a commercially available competitive enzyme-linked immunosorbent assay test kit. Repeat sampling was performed in seronegative animals to determine the incidence density rate from March through September (2013). Seroprevalence of heifers was significantly lower than that of cows at the beginning of the study (P < 0.001) but not at study completion (P = 0.075). Incidence density rate of Anaplasma marginale infection was 8.17 (95% confidence interval: 6.04, 10.81) cases per 1000 cow-days during the study period. Study cattle became Anaplasma marginale seropositive and likely carriers protected from severe clinical disease that might have occurred had they been first infected as mature adults. No evidence was found within this herd to suggest increased risk for clinical bovine erythrocytic anaplasmosis.

Original languageEnglish (US)
Article number6186078
JournalVeterinary Medicine International
Volume2016
DOIs
StatePublished - 2016

Fingerprint

Anaplasma marginale
Seroepidemiologic Studies
seroprevalence
beef
herds
incidence
anaplasmosis
Anaplasmosis
cattle
cows
Incidence
heifers
analytical kits
cattle diseases
Cattle Diseases
seroconversion
Angus
cohort studies
beef cattle
infection

ASJC Scopus subject areas

  • veterinary(all)

Cite this

@article{ca16325f66c04696bbc45509d12cbd5b,
title = "Investigation of Anaplasma marginale seroprevalence in a traditionally managed large California beef herd",
abstract = "Recent observations by stakeholders suggested that ecosystem changes may be driving an increased incidence of bovine erythrocytic anaplasmosis, resulting in a reemerging cattle disease in California. The objective of this prospective cohort study was to estimate the incidence of Anaplasma marginale infection using seroconversion in a northern California beef cattle herd. A total of 143 Black Angus cattle (106 prebreeding heifers and 37 cows) were enrolled in the study. Serum samples were collected to determine Anaplasma marginale seroprevalence using a commercially available competitive enzyme-linked immunosorbent assay test kit. Repeat sampling was performed in seronegative animals to determine the incidence density rate from March through September (2013). Seroprevalence of heifers was significantly lower than that of cows at the beginning of the study (P < 0.001) but not at study completion (P = 0.075). Incidence density rate of Anaplasma marginale infection was 8.17 (95{\%} confidence interval: 6.04, 10.81) cases per 1000 cow-days during the study period. Study cattle became Anaplasma marginale seropositive and likely carriers protected from severe clinical disease that might have occurred had they been first infected as mature adults. No evidence was found within this herd to suggest increased risk for clinical bovine erythrocytic anaplasmosis.",
author = "Tucker, {Thomas R.} and Aly, {Sharif S} and John Maas and Davy, {Josh S.} and Foley, {Janet E}",
year = "2016",
doi = "10.1155/2016/6186078",
language = "English (US)",
volume = "2016",
journal = "Veterinary Medicine International",
issn = "2090-8113",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Investigation of Anaplasma marginale seroprevalence in a traditionally managed large California beef herd

AU - Tucker, Thomas R.

AU - Aly, Sharif S

AU - Maas, John

AU - Davy, Josh S.

AU - Foley, Janet E

PY - 2016

Y1 - 2016

N2 - Recent observations by stakeholders suggested that ecosystem changes may be driving an increased incidence of bovine erythrocytic anaplasmosis, resulting in a reemerging cattle disease in California. The objective of this prospective cohort study was to estimate the incidence of Anaplasma marginale infection using seroconversion in a northern California beef cattle herd. A total of 143 Black Angus cattle (106 prebreeding heifers and 37 cows) were enrolled in the study. Serum samples were collected to determine Anaplasma marginale seroprevalence using a commercially available competitive enzyme-linked immunosorbent assay test kit. Repeat sampling was performed in seronegative animals to determine the incidence density rate from March through September (2013). Seroprevalence of heifers was significantly lower than that of cows at the beginning of the study (P < 0.001) but not at study completion (P = 0.075). Incidence density rate of Anaplasma marginale infection was 8.17 (95% confidence interval: 6.04, 10.81) cases per 1000 cow-days during the study period. Study cattle became Anaplasma marginale seropositive and likely carriers protected from severe clinical disease that might have occurred had they been first infected as mature adults. No evidence was found within this herd to suggest increased risk for clinical bovine erythrocytic anaplasmosis.

AB - Recent observations by stakeholders suggested that ecosystem changes may be driving an increased incidence of bovine erythrocytic anaplasmosis, resulting in a reemerging cattle disease in California. The objective of this prospective cohort study was to estimate the incidence of Anaplasma marginale infection using seroconversion in a northern California beef cattle herd. A total of 143 Black Angus cattle (106 prebreeding heifers and 37 cows) were enrolled in the study. Serum samples were collected to determine Anaplasma marginale seroprevalence using a commercially available competitive enzyme-linked immunosorbent assay test kit. Repeat sampling was performed in seronegative animals to determine the incidence density rate from March through September (2013). Seroprevalence of heifers was significantly lower than that of cows at the beginning of the study (P < 0.001) but not at study completion (P = 0.075). Incidence density rate of Anaplasma marginale infection was 8.17 (95% confidence interval: 6.04, 10.81) cases per 1000 cow-days during the study period. Study cattle became Anaplasma marginale seropositive and likely carriers protected from severe clinical disease that might have occurred had they been first infected as mature adults. No evidence was found within this herd to suggest increased risk for clinical bovine erythrocytic anaplasmosis.

UR - http://www.scopus.com/inward/record.url?scp=84987887222&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84987887222&partnerID=8YFLogxK

U2 - 10.1155/2016/6186078

DO - 10.1155/2016/6186078

M3 - Article

AN - SCOPUS:84987887222

VL - 2016

JO - Veterinary Medicine International

JF - Veterinary Medicine International

SN - 2090-8113

M1 - 6186078

ER -