@inproceedings{d74512d64d444ee0b2ac1b4309cbe815,
title = "Investigating the functional response of human cones and rods with a combined adaptive optics SLO-OCT system",
abstract = "In vivo functional imaging of human photoreceptors is an emerging field, with compelling potential applications in basic science, translational research, and clinical management of ophthalmic disease. Measurement of light-evoked changes in the cone photoreceptors has been successfully demonstrated using adaptive optics (AO) coherent flood illumination (CFI), AO scanning light ophthalmoscopy (SLO), AO optical coherence tomography (OCT), and full-field OCT with digital aberration correction (DAC). While the optical and computational principles of these systems differ greatly, and while these differences manifest in the resulting measurements, we believe that the approaches are all sensitive to light-evoked swelling of the cells. We describe a combined OCT-SLO with AO designed to measure this light-evoked swelling. In addition to OCT measurement of cone responses, we report their simultaneous OCT-SLO measurement as well as OCT measurement of rod photoreceptor function, neither of which, to our knowledge, have been reported before. ",
keywords = "Adaptive optics, Functional imaging, Optical coherence tomography (OCT), Optoretinogram, Optoretinography, Photoreceptors, Scanning light ophthalmoscope (SLO)",
author = "Mehdi Azimipour and Denise Valente and Vienola, {Kari V.} and Werner, {John S.} and Zawadzki, {Robert J.} and Jonnal, {Ravi S.}",
note = "Funding Information: We gratefully acknowledge the assistance of Susan Garcia, as well as funding from the National Eye Institute (NEI): R00-EY-026068(RSJ); R01-EY-026556(RJZ); R01 EY 024239(JSW).; 30th Conference on Ophthalmic Technologies ; Conference date: 01-02-2020 Through 02-02-2020",
year = "2020",
doi = "10.1117/12.2544462",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Fabrice Manns and Arthur Ho and Soderberg, {Per G.}",
booktitle = "Ophthalmic Technologies XXX",
}