Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

Wen Hong Fan, Mamta Parikh, John K. Snyder

Research output: Contribution to journalArticle

25 Scopus citations


β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

Original languageEnglish (US)
Pages (from-to)6591-6594
Number of pages4
JournalTetrahedron Letters
Issue number37
StatePublished - Jan 1 1995
Externally publishedYes


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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