Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

Wen Hong Fan, Mamta Parikh, John K. Snyder

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

Original languageEnglish (US)
Pages (from-to)6591-6594
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number37
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Carbolines
Thiourea
Cycloaddition
Cycloaddition Reaction
Electrons
Nitrogen
indole
1,2,4-triazine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines. / Fan, Wen Hong; Parikh, Mamta; Snyder, John K.

In: Tetrahedron Letters, Vol. 36, No. 37, 01.01.1995, p. 6591-6594.

Research output: Contribution to journalArticle

@article{ce35b62b4d3f44f78934b2d643cd8113,
title = "Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines",
abstract = "β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.",
author = "Fan, {Wen Hong} and Mamta Parikh and Snyder, {John K.}",
year = "1995",
month = "1",
day = "1",
doi = "10.1016/00404-0399(50)1347-K",
language = "English (US)",
volume = "36",
pages = "6591--6594",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "37",

}

TY - JOUR

T1 - Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

AU - Fan, Wen Hong

AU - Parikh, Mamta

AU - Snyder, John K.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

AB - β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

UR - http://www.scopus.com/inward/record.url?scp=0029143822&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029143822&partnerID=8YFLogxK

U2 - 10.1016/00404-0399(50)1347-K

DO - 10.1016/00404-0399(50)1347-K

M3 - Article

VL - 36

SP - 6591

EP - 6594

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 37

ER -