Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

Wen Hong Fan; Mamta Parikh; John K. Snyder

doi:10.1016/00404-0399(50)1347-K

Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

Wen Hong Fan, Mamta Parikh, John K. Snyder

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

Original language	English (US)
Pages (from-to)	6591-6594
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	37
DOIs	https://doi.org/10.1016/00404-0399(50)1347-K
State	Published - Jan 1 1995
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/00404-0399(50)1347-K

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title = "Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines",

abstract = "β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.",

author = "Fan, {Wen Hong} and Mamta Parikh and Snyder, {John K.}",

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AU - Parikh, Mamta

AU - Snyder, John K.

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Y1 - 1995/1/1

N2 - β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

AB - β-Carbolines have been prepared by the intramolecular cycloaddition of indole with 1,2,4-triazines tethered from C3 with the indolyl nitrogen using a thiourea linkage. Subsequent to the cycloaddition, reductive cleavage of the thiourea subunit provides the βcarboline.

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Inverse electron demand diels-alder reactions of indole IV. A new route to β-carbolines

Abstract

ASJC Scopus subject areas

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