Intravascular ultrasound with color-flow capability: Comparison with standard 2-D, color-flow and doppler echocardiography

Milind Dhond, Matthew O'Donnell, Michael Eberle, Douglas Stephens, Gerald Litzza, Danial Avaland, William J Bommer

Research output: Contribution to journalArticlepeer-review


To determine the usefulness of real time intravascular ultrasound (IVUS) with color-flow capability (Endosonics), we compared this technique to standard 2D, color-flow and doppler echocardiography with in-vitro and in-vivo (2 dogs, rabbit) studies. Intravascular colorflo is a 64 element phased array IVUS imaging system with selectable color-coded motion detection. In-vitro results: Intravascular colorflo provided higher spacial and flow resolution than standard 2-D and color-flow imaging and demonstrated progressive intensity and color-scale changes at velocities ranging from 7-82 cm/sec. In-vivo IVUS provided higher resolution imaging than standard transesophageal and external 2-D and color-flow imaging. Intravascular colorflo showed systolic variations with progressive color and intensity changes at velocities ranging from 0-40 cm/sec. and detected carotid flow cessation with vessel occlusion. The presence of phasic flow in adjacent vessels and contiguous flow in branch vessels was also seen. Conclusions: Intravascular colorflo appears to offer higher 2-D and color-flow resolution than transesophageal or external 2-D ultrasound. Real-time flow imaging may allow the operator to monitor blood flow and potential ischemia during interventional procedures. Its ability to navigate the vascular system may also allow certain catheterizations to be performed without the need for x-ray in patients with severe allergies or other adverse effects from contrast agents.

Original languageEnglish (US)
JournalJournal of Investigative Medicine
Issue number2
StatePublished - Feb 1999

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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