Intravascular Malignant T-cell Lymphoma (Malignant Angioendotheliomatosis) in a Cat

J. M. Lapointe, R. J. Higgins, G. D. Kortz, C. S. Bailey, P. F. Moore

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

A 7-year-old spayed female Siamese cat was presented with a 7-day history of ataxia, circling to the right, and involuntary micturition and defecation. Cerebrospinal fluid analysis showed increased protein content and relative eosinophilia. At necropsy, there was flattening of the cerebral cortical gyri of the right frontal and parietal lobes, and both kidneys had multiple wedge-shaped cortical indentations. Histologically, the cerebral cortex contained several extensive malacic foci, and the kidneys had multifocal parenchymal degeneration and atrophy. There was multifocal partial to complete thrombosis of renal interlobar arteries and of the right middle cerebral artery and meningeal branches; these thrombi contained large anaplastic round cells, which often invaded the arterial wall. Many smaller vessels within the kidneys and brain were occluded with clusters of similar cells, without thrombosis or vascular wall invasion. The neoplastic round cells had immunohistochemical staining properties of T lymphocytes.

Original languageEnglish (US)
Pages (from-to)247-250
Number of pages4
JournalVeterinary Pathology
Volume34
Issue number3
StatePublished - May 1997

Fingerprint

T-Cell Lymphoma
lymphoma
Cats
Thrombosis
T-lymphocytes
kidneys
cats
Kidney
thrombosis
arteries
Parietal Lobe
Defecation
Urination
Middle Cerebral Artery
Eosinophilia
Frontal Lobe
Renal Artery
Ataxia
Cerebral Cortex
eosinophilia

Keywords

  • Angioendotheliomatosis
  • Brain
  • Cats
  • CD3
  • Immunohistochemistry
  • Intravascular lymphoma
  • Kidney
  • T lymphocytes

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Intravascular Malignant T-cell Lymphoma (Malignant Angioendotheliomatosis) in a Cat. / Lapointe, J. M.; Higgins, R. J.; Kortz, G. D.; Bailey, C. S.; Moore, P. F.

In: Veterinary Pathology, Vol. 34, No. 3, 05.1997, p. 247-250.

Research output: Contribution to journalArticle

Lapointe, J. M. ; Higgins, R. J. ; Kortz, G. D. ; Bailey, C. S. ; Moore, P. F. / Intravascular Malignant T-cell Lymphoma (Malignant Angioendotheliomatosis) in a Cat. In: Veterinary Pathology. 1997 ; Vol. 34, No. 3. pp. 247-250.
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