Intraspecies and interspecies comparison of the compressive properties of the medial meniscus

M. A. Sweigart, C. F. Zhu, D. M. Burt, P. D. Deholl, C. M. Agrawal, T. O. Clanton, Kyriacos A. Athanasiou

Research output: Contribution to journalArticle

148 Citations (Scopus)

Abstract

Quantification of the compressive material properties of the meniscus is of paramount importance, creating a "gold-standard" reference for future research. The purpose of this study was to determine compressive properties in six animal models (baboon, bovine, canine, human, lapine, and porcine) at six topographical locations. It was hypothesized that topographical variation of the compressive properties would be found in each animal model and that interspecies variations would also be exhibited. To test these hypotheses, creep and recovery indentation experiments were performed on the meniscus using a creep indentation apparatus and analyzed via a finite element optimization method to determine the material properties. Results show significant intraspecies and interspecies variation in the compressive properties among the six topographical locations, with the moduli exhibiting the highest values in the anterior portion. For example, the anterior location of the human meniscus has an aggregate modulus of 160 ± 40 kPa, whereas the central and posterior portions exhibit aggregate moduli of 100 ± 30 kPa. Interspecies comparison of the aggregate moduli identifies the lapine anterior location having the highest value (450 ± 120 kPa) and the human posterior location having the lowest (100 ± 30 kPa). These baseline values of compressive properties will be of help in future meniscal repair efforts.

Original languageEnglish (US)
Pages (from-to)1569-1579
Number of pages11
JournalAnnals of Biomedical Engineering
Volume32
Issue number11
DOIs
StatePublished - Nov 2004
Externally publishedYes

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Indentation
Materials properties
Creep
Animals
Repair
Gold
Recovery
Experiments

Keywords

  • Biomechanics
  • Material properties
  • Meniscal cartilage

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Sweigart, M. A., Zhu, C. F., Burt, D. M., Deholl, P. D., Agrawal, C. M., Clanton, T. O., & Athanasiou, K. A. (2004). Intraspecies and interspecies comparison of the compressive properties of the medial meniscus. Annals of Biomedical Engineering, 32(11), 1569-1579. https://doi.org/10.1114/B:ABME.0000049040.70767.5c

Intraspecies and interspecies comparison of the compressive properties of the medial meniscus. / Sweigart, M. A.; Zhu, C. F.; Burt, D. M.; Deholl, P. D.; Agrawal, C. M.; Clanton, T. O.; Athanasiou, Kyriacos A.

In: Annals of Biomedical Engineering, Vol. 32, No. 11, 11.2004, p. 1569-1579.

Research output: Contribution to journalArticle

Sweigart, MA, Zhu, CF, Burt, DM, Deholl, PD, Agrawal, CM, Clanton, TO & Athanasiou, KA 2004, 'Intraspecies and interspecies comparison of the compressive properties of the medial meniscus', Annals of Biomedical Engineering, vol. 32, no. 11, pp. 1569-1579. https://doi.org/10.1114/B:ABME.0000049040.70767.5c
Sweigart, M. A. ; Zhu, C. F. ; Burt, D. M. ; Deholl, P. D. ; Agrawal, C. M. ; Clanton, T. O. ; Athanasiou, Kyriacos A. / Intraspecies and interspecies comparison of the compressive properties of the medial meniscus. In: Annals of Biomedical Engineering. 2004 ; Vol. 32, No. 11. pp. 1569-1579.
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