Intraperitoneal vaccination of pigs to control Mycoplasma hyopneumoniae

R. F. Sheldrake, Ian Gardner, M. M. Saunders, L. F. Romalis

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In a field trial at a commercial piggery 22 pigs were vaccinated intraperitoneally, at 30 days and 60 days old, with formalin-killed Mycoplasma hyopneumoniae plus adjuvant. Two other groups of the same size, one receiving a ration containing antibiotics, were not vaccinated. The mean enzyme-linked immunosorbent assay (elisa) ratio of the vaccinated group increased significantly (P<0·001) after 30 days, and continued to rise until day 156 of life. In the other two groups the elisa ratio did not increase significantly until day 115. The vaccinated pigs in the 30-day period after the first vaccination grew significantly (P<0·0·01) more slowly than the controls but between days 60 and 144 they grew significantly faster (P<0·05) than the two other groups, thus compensating for their previous, relative loss. At slaughter (at 163 days old), the mean weight was similar in all groups. The mean score for pneumonia at slaughter for the vaccinated, medicated and control groups was 2·6 (± 4·3), 9·4 (± 14·0) and 10·5 (± 12·4), respectively. The proportion of M hyopneumoniae-affected lungs (4·8 per cent) in vaccinated pigs, as judged by immunofluorescence, was significantly less (P<0·001) than the control groups (40 per cent). Thus, intraperitoneal vaccination with killed M hyopneumoniae plus adjuvant might control mycoplasmal pneumonia in commercial piggeries.

Original languageEnglish (US)
Pages (from-to)285-291
Number of pages7
JournalResearch in Veterinary Science
Volume51
Issue number3
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

Fingerprint

Mycoplasma hyopneumoniae
Vaccination
Swine
vaccination
pneumonia
swine
adjuvants
Pneumonia
slaughter
Enzyme-Linked Immunosorbent Assay
enzyme-linked immunosorbent assay
Control Groups
formalin
group size
Formaldehyde
fluorescent antibody technique
Fluorescent Antibody Technique
field experimentation
antibiotics
lungs

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Intraperitoneal vaccination of pigs to control Mycoplasma hyopneumoniae. / Sheldrake, R. F.; Gardner, Ian; Saunders, M. M.; Romalis, L. F.

In: Research in Veterinary Science, Vol. 51, No. 3, 01.01.1991, p. 285-291.

Research output: Contribution to journalArticle

Sheldrake, R. F. ; Gardner, Ian ; Saunders, M. M. ; Romalis, L. F. / Intraperitoneal vaccination of pigs to control Mycoplasma hyopneumoniae. In: Research in Veterinary Science. 1991 ; Vol. 51, No. 3. pp. 285-291.
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