Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine

Fuhai Ji; Hong Liu

doi:10.1007/s00540-013-1562-3

Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine

Fuhai Ji, Hong Liu

Anesthesiology and Pain Medicine

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

Hypernatremia and polyuria are the main symptoms of diabetes insipidus. Polyuria is characterized by a 24-h urine volume in excess of 40-50 ml/kg in adults. Dexmedetomidine, a highly selective, short-acting intravenous alpha-2 agonist, is used as a component of anesthesia, and has been suspected to induce polyuric syndrome. We report a patient who presented with severe hypernatremia and polyuria after intravenous infusion of dexmedetomidine.

Original language	English (US)
Pages (from-to)	599-603
Number of pages	5
Journal	Journal of Anesthesia
Volume	27
Issue number	4
DOIs	https://doi.org/10.1007/s00540-013-1562-3
State	Published - Aug 2013

Keywords

Dexmedetomidine
Diabetes insipidus
Hypernatremia
Polyuric syndrome

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

Access to Document

10.1007/s00540-013-1562-3

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Ji, F., & Liu, H. (2013). Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine. Journal of Anesthesia, 27(4), 599-603. https://doi.org/10.1007/s00540-013-1562-3

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AB - Hypernatremia and polyuria are the main symptoms of diabetes insipidus. Polyuria is characterized by a 24-h urine volume in excess of 40-50 ml/kg in adults. Dexmedetomidine, a highly selective, short-acting intravenous alpha-2 agonist, is used as a component of anesthesia, and has been suspected to induce polyuric syndrome. We report a patient who presented with severe hypernatremia and polyuria after intravenous infusion of dexmedetomidine.

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KW - Polyuric syndrome

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