Intramedullary lesions of the pediatric spinal cord: Correlation of findings from MR imaging, intraoperative sonography, surgery, and histologic study

James A Brunberg, Michael A. DiPietro, Joan L. Venes, Robert C. Dauser, Karin M. Muraszko, Gregory S. Berkey, Constance J. D'Amato, Jonathon M. Rubin

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Findings of preoperative magnetic resonance (MR) imaging and radiologist-directed intraoperative sonography (IOS) were correlated with surgical and pathologic findings in 11 pediatric patients with intramedullary spinal cord lesions. There were seven gliomas and one each of primitive neuroectodermal tumor, venous vascular malformation, neurenteric cyst, and active schistosomiasis. MR waging provided discrete preoperative anatomic localization and excluded multicentric lesions but did not reliably distinguish between solid and cystic lesions. IOS helped (a) define the limits of intramedullary mass before the dura mater was opened and (b) differentiate cystic from solid components. The internal architecture of intramedullary lesions, as shown with MR imaging and sonography, was strikingly similar, allowing discrete correlative localization for biopsy or tissue resection. Gadolinium-enhanced MR imaging and IOS are complementary imaging techniques that should be used in concert for the evaluation and management of intramedullary lesions of the pediatric spinal cord. Both techniques display regions of cord abnormality, but neither definitively characterizes underlying tissue histology.

Original languageEnglish (US)
Pages (from-to)573-579
Number of pages7
JournalRadiology
Volume181
Issue number2
StatePublished - Nov 1991
Externally publishedYes

Fingerprint

Ultrasonography
Spinal Cord
Magnetic Resonance Imaging
Pediatrics
Primitive Neuroectodermal Tumors
Dura Mater
Vascular Malformations
Neural Tube Defects
Schistosomiasis
Gadolinium
Glioma
Histology
Magnetic Resonance Spectroscopy
Biopsy

Keywords

  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement, 351.12988
  • Schistosomiasis, 351.2084
  • Spinal cord, cysts, 551.2084, 351.3611
  • Spinal cord, MR studies, 341.1214, 351.1214
  • Spinal cord, neoplasms, 341.3632, 341.3636, 351.3632, 351.3635, 351.365

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Brunberg, J. A., DiPietro, M. A., Venes, J. L., Dauser, R. C., Muraszko, K. M., Berkey, G. S., ... Rubin, J. M. (1991). Intramedullary lesions of the pediatric spinal cord: Correlation of findings from MR imaging, intraoperative sonography, surgery, and histologic study. Radiology, 181(2), 573-579.

Intramedullary lesions of the pediatric spinal cord : Correlation of findings from MR imaging, intraoperative sonography, surgery, and histologic study. / Brunberg, James A; DiPietro, Michael A.; Venes, Joan L.; Dauser, Robert C.; Muraszko, Karin M.; Berkey, Gregory S.; D'Amato, Constance J.; Rubin, Jonathon M.

In: Radiology, Vol. 181, No. 2, 11.1991, p. 573-579.

Research output: Contribution to journalArticle

Brunberg, JA, DiPietro, MA, Venes, JL, Dauser, RC, Muraszko, KM, Berkey, GS, D'Amato, CJ & Rubin, JM 1991, 'Intramedullary lesions of the pediatric spinal cord: Correlation of findings from MR imaging, intraoperative sonography, surgery, and histologic study', Radiology, vol. 181, no. 2, pp. 573-579.
Brunberg, James A ; DiPietro, Michael A. ; Venes, Joan L. ; Dauser, Robert C. ; Muraszko, Karin M. ; Berkey, Gregory S. ; D'Amato, Constance J. ; Rubin, Jonathon M. / Intramedullary lesions of the pediatric spinal cord : Correlation of findings from MR imaging, intraoperative sonography, surgery, and histologic study. In: Radiology. 1991 ; Vol. 181, No. 2. pp. 573-579.
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