Intracranial meningioma with pulmonary metastasis in three dogs.

F. Y. Schulman, J. L. Ribas, J. L. Carpenter, A. F. Sisson, Richard A Lecouteur

Research output: Contribution to journalArticle

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Abstract

Extracranial metastasis of primary central nervous system neoplasms is uncommon and has not been described in the dog. We report the clincopathologic features of intracranial meningioma with pulmonary metastasis in three dogs (case No. 1: 13-year-old castrated male Boxer dog; case No. 2: 14-year-old spayed female Dachshund; case No. 3: 6-year-old spayed female German Shepherd Dog). Case No. 1 presented with ataxia, lethargy, vomiting, and leaning and falling to the right, and had a transient remission following radiation and corticosteroid therapy; case No. 2 had a history of seizures that were unresponsive to primidone, left-sided postural reaction deficits, ataxia, and circling to the right; case No. 3 had only intermittent episodes of vomiting Computed tomography of case Nos. 1 and 2 revealed peripherally located homogeneous contrast-enhancing intracranial masses. Postmortem examination revealed intracranial masses with single or multiple pulmonary nodules in all three cases. Histologically, the intracranial and pulmonary masses were meningotheliomatous meningiomas with atypical features including brain infiltration, necrosis, nuclear atypia, prominent nucleoli, and moderate cell density. All of the primary meningiomas had low mitotic rates. The current interest in early diagnosis and aggressive clinical/surgical management of canine patients with meningioma and other primary central nervous system neoplasms will likely result in an increased detection of extracranial metastases.

Original languageEnglish (US)
Pages (from-to)196-202
Number of pages7
JournalVeterinary Pathology
Volume29
Issue number3
StatePublished - May 1992
Externally publishedYes

Fingerprint

Meningioma
metastasis
lungs
Dogs
Neoplasm Metastasis
Central Nervous System Neoplasms
Lung
dogs
Ataxia
Vomiting
vomiting
Multiple Pulmonary Nodules
Primidone
central nervous system
Lethargy
Dachshund
Boxer (dog breed)
neoplasms
German Shepherd
early diagnosis

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Schulman, F. Y., Ribas, J. L., Carpenter, J. L., Sisson, A. F., & Lecouteur, R. A. (1992). Intracranial meningioma with pulmonary metastasis in three dogs. Veterinary Pathology, 29(3), 196-202.

Intracranial meningioma with pulmonary metastasis in three dogs. / Schulman, F. Y.; Ribas, J. L.; Carpenter, J. L.; Sisson, A. F.; Lecouteur, Richard A.

In: Veterinary Pathology, Vol. 29, No. 3, 05.1992, p. 196-202.

Research output: Contribution to journalArticle

Schulman, FY, Ribas, JL, Carpenter, JL, Sisson, AF & Lecouteur, RA 1992, 'Intracranial meningioma with pulmonary metastasis in three dogs.', Veterinary Pathology, vol. 29, no. 3, pp. 196-202.
Schulman FY, Ribas JL, Carpenter JL, Sisson AF, Lecouteur RA. Intracranial meningioma with pulmonary metastasis in three dogs. Veterinary Pathology. 1992 May;29(3):196-202.
Schulman, F. Y. ; Ribas, J. L. ; Carpenter, J. L. ; Sisson, A. F. ; Lecouteur, Richard A. / Intracranial meningioma with pulmonary metastasis in three dogs. In: Veterinary Pathology. 1992 ; Vol. 29, No. 3. pp. 196-202.
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