Intra-Arterial Reteplase for the Treatment of Acute Limb Ischemia

John R. Laird

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The removal of urokinase from the market has created a dilemma for interventionists and vascular surgeons treating patients with acute limb threatening ischemia due to arterial thrombosis or embolization. Reteplase is a newer, fibrin-specific thrombolytic agent with properties that make it an attractive alternative to urokinase. We report two cases of successful treatment of acute, limb threatening ischemia with intra-arterial Reteplase therapy.

Original languageEnglish (US)
Pages (from-to)757-762
Number of pages6
JournalJournal of Invasive Cardiology
Issue number12
StatePublished - 1999
Externally publishedYes


  • Peripheral vascular disease
  • Thrombolysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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