Intestinal neoplasia in horses

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Background: Intestinal neoplasia of horses is inadequately described. Hypothesis: Intestinal neoplasia of horses has characteristic clinicopathologic features. Animals: Thirty-four horses with intestinal neoplasia. Methods: Retrospective study. Results: Anamnesis, clinical signs, clinicopathologic and pathologic findings in 34 adult horses diagnosed histologically with intestinal neoplasia were reviewed. The horses ranged in age from 2 to 30 years (mean 16.6 years at presentation). The Arabian breed was most represented and there was no sex predisposition. The most common presenting complaints were weight loss, colic, anorexia, and fever. The most consistent clinical signs were poor body condition, tachycardia, tachypnea, fever, and diarrhea. Useful diagnostic tools included rectal examination, routine blood analyses, abdominocentesis, ultrasonographic examination, rectal biopsy, and exploratory laparotomy. Alimentary lymphoma was the most common intestinal neoplasia identified, followed by adenocarcinoma and smooth muscle tumors. The small intestine was the most common segment of intestine affected for all neoplasms. Intestinal neoplasia was diagnosed antemortem in 13 of 34 (38%) horses. The median time from onset of clinical signs to death or euthanasia was 1.9 months. The discharge rate was 15%. Although the longest survival was observed in horses with jejunal adenocarcinoma, all horses were eventually euthanized because of intestinal neoplasia. Conclusions: Arabian horses were 4.5 times more likely to have intestinal neoplasia diagnosed than were other breeds.

Original languageEnglish (US)
Pages (from-to)1429-1436
Number of pages8
JournalJournal of Veterinary Internal Medicine
Volume20
Issue number6
DOIs
StatePublished - Nov 2006

Fingerprint

Horses
horses
neoplasms
Neoplasms
Arabian (horse breed)
adenocarcinoma
fever
Adenocarcinoma
Fever
Smooth Muscle Tumor
Tachypnea
breeds
Euthanasia
Colic
Anorexia
laparotomy
colic
Tachycardia
euthanasia
Laparotomy

Keywords

  • Adenocarcinoma
  • Alimentary lymphoma
  • Horse
  • Intestinal neoplasia
  • Lymphosarcoma
  • Smooth muscle tumors

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Intestinal neoplasia in horses. / Taylor, S. D.; Pusterla, Nicola; Vaughan, Mary E; Whitcomb, Mary B; Wilson, William D.

In: Journal of Veterinary Internal Medicine, Vol. 20, No. 6, 11.2006, p. 1429-1436.

Research output: Contribution to journalArticle

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