Abstract
New research has identified specific intestinal colonizing microbes that can have significant influence on health and disease. Evidence is reviewed supporting an association between Fusobacterium nucleatum and colon cancer and for a protective role of Faecalibacterium prausnitzii in inflammatory bowel disease, of Escherichia coli Nissle 1917 in acute intestinal inflammation, of Bifidobacterium infantis in neonatal necrotizing enterocolitis, and of Akkermansia muciniphila in obesity and diabetes. These novel bacteria are clinically relevant and present opportunities for more focused diagnosis of colon cancer and prevention of common diseases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 133-137 |
| Number of pages | 5 |
| Journal | Preventive Medicine |
| Volume | 65 |
| DOIs | |
| State | Published - 2014 |
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Keywords
- Acute intestinal inflammation
- Akkermansia muciniphila
- Bifidobacterium infantis
- Colon cancer
- Escherichia coli Nissle 1917
- Faecalibacterium prausnitzii
- Fusobacterium nucleatum
- Inflammatory bowel disease
- Necrotizing enterocolitis
- Obesity
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Epidemiology
Cite this
Intestinal dysbiosis : Novel mechanisms by which gut microbes trigger and prevent disease. / Underwood, Mark.
In: Preventive Medicine, Vol. 65, 2014, p. 133-137.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intestinal dysbiosis
T2 - Novel mechanisms by which gut microbes trigger and prevent disease
AU - Underwood, Mark
PY - 2014
Y1 - 2014
N2 - New research has identified specific intestinal colonizing microbes that can have significant influence on health and disease. Evidence is reviewed supporting an association between Fusobacterium nucleatum and colon cancer and for a protective role of Faecalibacterium prausnitzii in inflammatory bowel disease, of Escherichia coli Nissle 1917 in acute intestinal inflammation, of Bifidobacterium infantis in neonatal necrotizing enterocolitis, and of Akkermansia muciniphila in obesity and diabetes. These novel bacteria are clinically relevant and present opportunities for more focused diagnosis of colon cancer and prevention of common diseases.
AB - New research has identified specific intestinal colonizing microbes that can have significant influence on health and disease. Evidence is reviewed supporting an association between Fusobacterium nucleatum and colon cancer and for a protective role of Faecalibacterium prausnitzii in inflammatory bowel disease, of Escherichia coli Nissle 1917 in acute intestinal inflammation, of Bifidobacterium infantis in neonatal necrotizing enterocolitis, and of Akkermansia muciniphila in obesity and diabetes. These novel bacteria are clinically relevant and present opportunities for more focused diagnosis of colon cancer and prevention of common diseases.
KW - Acute intestinal inflammation
KW - Akkermansia muciniphila
KW - Bifidobacterium infantis
KW - Colon cancer
KW - Escherichia coli Nissle 1917
KW - Faecalibacterium prausnitzii
KW - Fusobacterium nucleatum
KW - Inflammatory bowel disease
KW - Necrotizing enterocolitis
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=84901491205&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901491205&partnerID=8YFLogxK
U2 - 10.1016/j.ypmed.2014.05.010
DO - 10.1016/j.ypmed.2014.05.010
M3 - Article
C2 - 24857830
AN - SCOPUS:84901491205
VL - 65
SP - 133
EP - 137
JO - Preventive Medicine
JF - Preventive Medicine
SN - 0091-7435
ER -