International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments

on behalf of the Pediatric Emergency Research Networks (PERN) Poisoning Working Group

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: Identifying international differences in the epidemiology of acute poisonings in children may help in improving prevention. We sought to evaluate the international epidemiological differences in acute poisonings in children presenting to emergency departments (EDs) from 8 different global regions. METHODS: This was an international multicenter cross-sectional prospective study including children younger than 18 years with acute poisonings presenting to 105 EDs in 20 countries was conducted. Data collection started at each ED between January and September 2013, and continued for 1 year. RESULTS: During the study period, we registered 363,245 pediatric ED presentations, of which 1727 were for poisoning (0.47%; 95% confidence interval, 0.45%–0.50%), with a significant variation in incidence between the regions. Full data were obtained for 1688 presentations. Most poisonings (1361 [80.6%]) occurred at home with either ingestion (1504 [89.0%]) or inhalation of the toxin (126 [7.6%]). Nonintentional exposures accounted for 1157 poisonings (68.5%; mainly in South America and Eastern Mediterranean region), with therapeutic drugs (494 [42.7%]), household products (310 [26.8%]), and pesticides (59 [5.1%]) being the most common toxins. Suicide attempts accounted for 233 exposures (13.8%; mainly in the Western Pacific region and North America), with therapeutic drugs (214 [91.8%], mainly psychotropics and acetaminophen) being the most common toxins. Significant differences between regions were found in both types of poisonings. Recreational poisonings were more common in Europe and Western Pacific region. No patient died. CONCLUSIONS: There are substantial epidemiological differences in acute poisonings among children in different countries and regions of the globe. International best practices need to be identified for prevention of acute poisonings in childhood.

Original languageEnglish (US)
JournalPediatric Emergency Care
DOIs
StateAccepted/In press - Jan 24 2017

Fingerprint

Poisoning
Hospital Emergency Service
Pediatrics
Household Products
Mediterranean Region
South America
Acetaminophen
North America
Practice Guidelines
Pesticides
Pharmaceutical Preparations
Suicide
Inhalation
Epidemiology
Cross-Sectional Studies
Eating
Prospective Studies
Confidence Intervals
Incidence
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

Cite this

on behalf of the Pediatric Emergency Research Networks (PERN) Poisoning Working Group (Accepted/In press). International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. Pediatric Emergency Care. https://doi.org/10.1097/PEC.0000000000001031

International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. / on behalf of the Pediatric Emergency Research Networks (PERN) Poisoning Working Group.

In: Pediatric Emergency Care, 24.01.2017.

Research output: Contribution to journalArticle

on behalf of the Pediatric Emergency Research Networks (PERN) Poisoning Working Group. / International Epidemiological Differences in Acute Poisonings in Pediatric Emergency Departments. In: Pediatric Emergency Care. 2017.
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abstract = "BACKGROUND AND OBJECTIVE: Identifying international differences in the epidemiology of acute poisonings in children may help in improving prevention. We sought to evaluate the international epidemiological differences in acute poisonings in children presenting to emergency departments (EDs) from 8 different global regions. METHODS: This was an international multicenter cross-sectional prospective study including children younger than 18 years with acute poisonings presenting to 105 EDs in 20 countries was conducted. Data collection started at each ED between January and September 2013, and continued for 1 year. RESULTS: During the study period, we registered 363,245 pediatric ED presentations, of which 1727 were for poisoning (0.47{\%}; 95{\%} confidence interval, 0.45{\%}–0.50{\%}), with a significant variation in incidence between the regions. Full data were obtained for 1688 presentations. Most poisonings (1361 [80.6{\%}]) occurred at home with either ingestion (1504 [89.0{\%}]) or inhalation of the toxin (126 [7.6{\%}]). Nonintentional exposures accounted for 1157 poisonings (68.5{\%}; mainly in South America and Eastern Mediterranean region), with therapeutic drugs (494 [42.7{\%}]), household products (310 [26.8{\%}]), and pesticides (59 [5.1{\%}]) being the most common toxins. Suicide attempts accounted for 233 exposures (13.8{\%}; mainly in the Western Pacific region and North America), with therapeutic drugs (214 [91.8{\%}], mainly psychotropics and acetaminophen) being the most common toxins. Significant differences between regions were found in both types of poisonings. Recreational poisonings were more common in Europe and Western Pacific region. No patient died. CONCLUSIONS: There are substantial epidemiological differences in acute poisonings among children in different countries and regions of the globe. International best practices need to be identified for prevention of acute poisonings in childhood.",
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AU - Azkunaga, Beatriz

AU - Prego, Javier

AU - Qureshi, Nadeem

AU - Dalziel, Stuart R.

AU - Arana-Arri, Eunate

AU - Acedo, Yordana

AU - Martinez-Indart, Lorea

AU - Urkaregi, Arantza

AU - Salmon, Nerea

AU - Benito, Javier

AU - Kuppermann, Nathan

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N2 - BACKGROUND AND OBJECTIVE: Identifying international differences in the epidemiology of acute poisonings in children may help in improving prevention. We sought to evaluate the international epidemiological differences in acute poisonings in children presenting to emergency departments (EDs) from 8 different global regions. METHODS: This was an international multicenter cross-sectional prospective study including children younger than 18 years with acute poisonings presenting to 105 EDs in 20 countries was conducted. Data collection started at each ED between January and September 2013, and continued for 1 year. RESULTS: During the study period, we registered 363,245 pediatric ED presentations, of which 1727 were for poisoning (0.47%; 95% confidence interval, 0.45%–0.50%), with a significant variation in incidence between the regions. Full data were obtained for 1688 presentations. Most poisonings (1361 [80.6%]) occurred at home with either ingestion (1504 [89.0%]) or inhalation of the toxin (126 [7.6%]). Nonintentional exposures accounted for 1157 poisonings (68.5%; mainly in South America and Eastern Mediterranean region), with therapeutic drugs (494 [42.7%]), household products (310 [26.8%]), and pesticides (59 [5.1%]) being the most common toxins. Suicide attempts accounted for 233 exposures (13.8%; mainly in the Western Pacific region and North America), with therapeutic drugs (214 [91.8%], mainly psychotropics and acetaminophen) being the most common toxins. Significant differences between regions were found in both types of poisonings. Recreational poisonings were more common in Europe and Western Pacific region. No patient died. CONCLUSIONS: There are substantial epidemiological differences in acute poisonings among children in different countries and regions of the globe. International best practices need to be identified for prevention of acute poisonings in childhood.

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