Interferon-γ: A key immunoregulatory lymphokine

John G. Williams; Gregory Jurkovich; Ronald V. Maier

doi:10.1006/jsre.1993.1013

Interferon-γ: A key immunoregulatory lymphokine

John G. Williams, Gregory Jurkovich, Ronald V. Maier

Research output: Contribution to journal › Review article

71 Scopus citations

Abstract

Interferon-γ is an important component of numerous host responses to inflammatory insults. Data from in vitro and animal studies suggest that this agent may have clinical uses in immunocompromised patients who are at increased risk for infectious complications. In addition to reviewing our current understanding of the in vitro and in vivo actions of interferon-γ, this article cautions that the potential for adverse reactions exists when interferon-γ is administered to an immunologically competent host.

Original language	English (US)
Pages (from-to)	79-93
Number of pages	15
Journal	Journal of Surgical Research
Volume	54
Issue number	1
DOIs	https://doi.org/10.1006/jsre.1993.1013
State	Published - Jan 1 1993
Externally published	Yes

ASJC Scopus subject areas

Surgery

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Williams, J. G., Jurkovich, G., & Maier, R. V. (1993). Interferon-γ: A key immunoregulatory lymphokine. Journal of Surgical Research, 54(1), 79-93. https://doi.org/10.1006/jsre.1993.1013

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