Intake fraction for multimedia pollutants: A tool for life cycle analysis and comparative risk assessment

Deborah H Bennett, Manuele D. Margni, Thomas E. McKone, Olivier Jolliet

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

We employ the intake fraction (iF) as an effective tool for expressing the source-to-intake relationship for pollutant emissions in life cycle analysis (LCA) or comparative risk assessment. Intake fraction is the fraction of chemical mass emitted into the environment that eventually passes into a member of the population through inhalation, ingestion, or dermal exposure. To date, this concept has been primarily applied to pollutants whose primary route of exposure is inhalation. Here we extend the use of iF to multimedia pollutants with multiple exposure pathways. We use a level III multimedia model to calculate iF for TCDD and compare the result to one calculated from measured levels of dioxin toxic equivalents in the environment. We calculate iF for emissions to air and surface water for 308 chemicals. We correlate the primary exposure route with the magnitudes of the octanol-water partition coefficient, K ow, and of the air-water partitioning coefficient (dimensionless Henry constant), K aw. This results in value ranges of K ow and K aw where the chemical exposure route can be classified with limited input data requirements as primarily inhalation, primarily ingestion, or multipathway. For the inhalation and ingestion dominant pollutants, we also define empirical relationships based on chemical properties for quantifying the intake fraction. The empirical relationships facilitate rapid evaluation of many chemicals in terms of the intake. By defining a theoretical upper limit for iF in a multimedia environment we find that iF calculations provide insight into the multimedia model algorithms and help identify unusual patterns of exposure and questionable exposure model results.

Original languageEnglish (US)
Pages (from-to)905-918
Number of pages14
JournalRisk Analysis
Volume22
Issue number5
DOIs
StatePublished - Oct 2002
Externally publishedYes

Fingerprint

Multimedia
Life Cycle Stages
pollutant
life cycle
Risk assessment
risk assessment
multimedia
Life cycle
Inhalation
Eating
water
Water
Air
air
Inhalation Exposure
Octanols
Dioxins
Poisons
Surface waters
Chemical properties

Keywords

  • Comparative risk assessment
  • Exposure
  • Intake fraction
  • Life cycle analysis
  • Multimedia modeling

ASJC Scopus subject areas

  • Social Sciences (miscellaneous)
  • Safety, Risk, Reliability and Quality

Cite this

Intake fraction for multimedia pollutants : A tool for life cycle analysis and comparative risk assessment. / Bennett, Deborah H; Margni, Manuele D.; McKone, Thomas E.; Jolliet, Olivier.

In: Risk Analysis, Vol. 22, No. 5, 10.2002, p. 905-918.

Research output: Contribution to journalArticle

Bennett, Deborah H ; Margni, Manuele D. ; McKone, Thomas E. ; Jolliet, Olivier. / Intake fraction for multimedia pollutants : A tool for life cycle analysis and comparative risk assessment. In: Risk Analysis. 2002 ; Vol. 22, No. 5. pp. 905-918.
@article{a692da8cf79e4f6c9bd29f2d9f276673,
title = "Intake fraction for multimedia pollutants: A tool for life cycle analysis and comparative risk assessment",
abstract = "We employ the intake fraction (iF) as an effective tool for expressing the source-to-intake relationship for pollutant emissions in life cycle analysis (LCA) or comparative risk assessment. Intake fraction is the fraction of chemical mass emitted into the environment that eventually passes into a member of the population through inhalation, ingestion, or dermal exposure. To date, this concept has been primarily applied to pollutants whose primary route of exposure is inhalation. Here we extend the use of iF to multimedia pollutants with multiple exposure pathways. We use a level III multimedia model to calculate iF for TCDD and compare the result to one calculated from measured levels of dioxin toxic equivalents in the environment. We calculate iF for emissions to air and surface water for 308 chemicals. We correlate the primary exposure route with the magnitudes of the octanol-water partition coefficient, K ow, and of the air-water partitioning coefficient (dimensionless Henry constant), K aw. This results in value ranges of K ow and K aw where the chemical exposure route can be classified with limited input data requirements as primarily inhalation, primarily ingestion, or multipathway. For the inhalation and ingestion dominant pollutants, we also define empirical relationships based on chemical properties for quantifying the intake fraction. The empirical relationships facilitate rapid evaluation of many chemicals in terms of the intake. By defining a theoretical upper limit for iF in a multimedia environment we find that iF calculations provide insight into the multimedia model algorithms and help identify unusual patterns of exposure and questionable exposure model results.",
keywords = "Comparative risk assessment, Exposure, Intake fraction, Life cycle analysis, Multimedia modeling",
author = "Bennett, {Deborah H} and Margni, {Manuele D.} and McKone, {Thomas E.} and Olivier Jolliet",
year = "2002",
month = "10",
doi = "10.1111/1539-6924.00260",
language = "English (US)",
volume = "22",
pages = "905--918",
journal = "Risk Analysis",
issn = "0272-4332",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Intake fraction for multimedia pollutants

T2 - A tool for life cycle analysis and comparative risk assessment

AU - Bennett, Deborah H

AU - Margni, Manuele D.

AU - McKone, Thomas E.

AU - Jolliet, Olivier

PY - 2002/10

Y1 - 2002/10

N2 - We employ the intake fraction (iF) as an effective tool for expressing the source-to-intake relationship for pollutant emissions in life cycle analysis (LCA) or comparative risk assessment. Intake fraction is the fraction of chemical mass emitted into the environment that eventually passes into a member of the population through inhalation, ingestion, or dermal exposure. To date, this concept has been primarily applied to pollutants whose primary route of exposure is inhalation. Here we extend the use of iF to multimedia pollutants with multiple exposure pathways. We use a level III multimedia model to calculate iF for TCDD and compare the result to one calculated from measured levels of dioxin toxic equivalents in the environment. We calculate iF for emissions to air and surface water for 308 chemicals. We correlate the primary exposure route with the magnitudes of the octanol-water partition coefficient, K ow, and of the air-water partitioning coefficient (dimensionless Henry constant), K aw. This results in value ranges of K ow and K aw where the chemical exposure route can be classified with limited input data requirements as primarily inhalation, primarily ingestion, or multipathway. For the inhalation and ingestion dominant pollutants, we also define empirical relationships based on chemical properties for quantifying the intake fraction. The empirical relationships facilitate rapid evaluation of many chemicals in terms of the intake. By defining a theoretical upper limit for iF in a multimedia environment we find that iF calculations provide insight into the multimedia model algorithms and help identify unusual patterns of exposure and questionable exposure model results.

AB - We employ the intake fraction (iF) as an effective tool for expressing the source-to-intake relationship for pollutant emissions in life cycle analysis (LCA) or comparative risk assessment. Intake fraction is the fraction of chemical mass emitted into the environment that eventually passes into a member of the population through inhalation, ingestion, or dermal exposure. To date, this concept has been primarily applied to pollutants whose primary route of exposure is inhalation. Here we extend the use of iF to multimedia pollutants with multiple exposure pathways. We use a level III multimedia model to calculate iF for TCDD and compare the result to one calculated from measured levels of dioxin toxic equivalents in the environment. We calculate iF for emissions to air and surface water for 308 chemicals. We correlate the primary exposure route with the magnitudes of the octanol-water partition coefficient, K ow, and of the air-water partitioning coefficient (dimensionless Henry constant), K aw. This results in value ranges of K ow and K aw where the chemical exposure route can be classified with limited input data requirements as primarily inhalation, primarily ingestion, or multipathway. For the inhalation and ingestion dominant pollutants, we also define empirical relationships based on chemical properties for quantifying the intake fraction. The empirical relationships facilitate rapid evaluation of many chemicals in terms of the intake. By defining a theoretical upper limit for iF in a multimedia environment we find that iF calculations provide insight into the multimedia model algorithms and help identify unusual patterns of exposure and questionable exposure model results.

KW - Comparative risk assessment

KW - Exposure

KW - Intake fraction

KW - Life cycle analysis

KW - Multimedia modeling

UR - http://www.scopus.com/inward/record.url?scp=0036772911&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036772911&partnerID=8YFLogxK

U2 - 10.1111/1539-6924.00260

DO - 10.1111/1539-6924.00260

M3 - Article

C2 - 12442988

AN - SCOPUS:0036772911

VL - 22

SP - 905

EP - 918

JO - Risk Analysis

JF - Risk Analysis

SN - 0272-4332

IS - 5

ER -