Insulin response to oral glucose in young, non-obese Indian males with myocardial infarction

M. Sewdarsen, I. Jialal, S. Vythilingum

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Plasma glucose and insulin concentrations were estimated during an oral glucose tolerance test (OGTT) in a group of 25 young (< 40 years), non-obese Indian males 6-12 months after an episode of acute myocardial infarction and in 25 age- and sex-matched controls. All the subjects in both groups had a normal response to the OGTT according to the 1980 World Health Organization criteria. Glucose values during the OGTT and the mean plasma insulin response were significantly higher in the patients who had had a myocardial infarction. However, there was no significant difference in the insulinogenic indices. These findings indicate that Indian patients with myocardial infarction have aberrations in carbohydrate metabolism which manifest as higher glucose values during an OGTT and that the stimulated hyperinsulinism is secondary to these raised glucose levels.

Original languageEnglish (US)
Pages (from-to)523-525
Number of pages3
JournalSouth African Medical Journal
Issue number14
StatePublished - 1984
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

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