Insulin resistance and hypertension: Therapeutic implications

Research output: Contribution to journalArticlepeer-review


Historical and current evidence demonstrate that insulin resistance is a feature of essential hypertension. Evidence also suggests that insulin resistance is related to coronary risk factors other than hypertension. Although insulin resistance may be an inborn characteristic, it responds to a variety of interventions that may also ameliorate hypertension. In particular, various antihypertensive regimens impact differently on insulin resistance. It may be possible to design drug regimens that exploit the metabolic, rather than the purely hemodynamic, consequences of antihypertensive therapy.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalDrug Therapy
Issue number6
StatePublished - 1992

ASJC Scopus subject areas

  • Pharmaceutical Science


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