Insulin resistance and hypertension

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


The author has reviewed the development of the concept that insulin resistance is related not only to the hypertensive state but potentially to the initiation and maintenance of high blood pressure. Potential sequelae of insulin resistance and hyperinsulinemia, as they apply to atherogenesis, are also discussed. The impact of present antihypertensive pharmacologic therapy on insulin resistance is addressed, as are future directions in pharmacologic and nonpharmacologic management of hypertension. In addition, the author speculates on possible mechanisms leading to insulin resistance in hypertension.

Original languageEnglish (US)
Pages (from-to)104-115
Number of pages12
JournalAmerican Journal of the Medical Sciences
Issue number2
StatePublished - 1990
Externally publishedYes


  • Glucose tolerance
  • Hypertension
  • Hypertensive therapy
  • Insulin resistance

ASJC Scopus subject areas

  • Medicine(all)


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