Ins and outs of cellular cobalamin transport

Ralph Green

doi:10.1182/blood-2009-12-254037

Ins and outs of cellular cobalamin transport

Ralph Green

Pathology and Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Quite a bit is now known about the complex mechanisms underlying how Cbl gets into cells. Just how the vitamin gets out for recycling remained a mystery until the findings by Beedholm-Ebsen and colleagues. In their article in this issue of Blood, cellular egress of Cbl is shown to occur by transport of "free" Cbl via the ABC drug transporter, ABCC1 (also known as the MRP1), present in the basolateral membrane of intestinal epithelium and in other cells.

Original language	English (US)
Pages (from-to)	1476-1477
Number of pages	2
Journal	Blood
Volume	115
Issue number	8
DOIs	https://doi.org/10.1182/blood-2009-12-254037
State	Published - Feb 25 2010

ASJC Scopus subject areas

Hematology
Biochemistry
Cell Biology
Immunology

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Ins and outs of cellular cobalamin transport

Abstract

ASJC Scopus subject areas

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