Abstract
The uptake of radiolabeled myo-inositol by Schwann cells isolated from the sciatic nerve of 2-4 day old rats was found to occur by a saturable, sodium-dependent phlorizin-inhibited mechanism with an estimated Km of 30μM. The system was inhibited by galactose and glucose but not by galactitol. At high concentrations of myo-inositol, a diffusion-like process appeared to be functional. The characteristics of the saturable system are very similar to those of myo-inositol uptake by the endoneural fascicle preparation of sciatic nerve.
Original language | English (US) |
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Pages (from-to) | 486-492 |
Number of pages | 7 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 120 |
Issue number | 2 |
DOIs | |
State | Published - Apr 30 1984 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology