TY - JOUR
T1 - Initial report of bladder carcinoma following combined bladder-drained pancreas and kidney transplantation
AU - Highshaw, Ralph A.
AU - Tunuguntla, Hari S G R
AU - Perez, Richard V.
AU - Gandour-Edwards, Regina
AU - Evans, Christopher P.
PY - 2002/10
Y1 - 2002/10
N2 - Although long-term survival of a functional allograft requiring long-term immunosuppressive therapy is responsible for higher incidence of non-urothelial cancers in renal allograft recipients than in normal population, the incidence of bladder cancer is uncommon and carcinoma of the bladder in the setting of combined kidney-pancreas transplantation has not been reported to date. We herein report a case of poorly differentiated invasive adeno-squamous cell carcinoma of the bladder following renal and bladder-drained pancreatic transplantation in a 44-yr-old lady with long-standing insulin dependent diabetes mellitus, which necessitated radical extirpation. Management implications are reviewed.
AB - Although long-term survival of a functional allograft requiring long-term immunosuppressive therapy is responsible for higher incidence of non-urothelial cancers in renal allograft recipients than in normal population, the incidence of bladder cancer is uncommon and carcinoma of the bladder in the setting of combined kidney-pancreas transplantation has not been reported to date. We herein report a case of poorly differentiated invasive adeno-squamous cell carcinoma of the bladder following renal and bladder-drained pancreatic transplantation in a 44-yr-old lady with long-standing insulin dependent diabetes mellitus, which necessitated radical extirpation. Management implications are reviewed.
KW - Adeno-squamous carcinoma
KW - Carcinogenesis
KW - Cytology
KW - Hematuria
KW - Kidney
KW - Pancreas transplantation
KW - Transitional cell carcinoma
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UR - http://www.scopus.com/inward/citedby.url?scp=0036786197&partnerID=8YFLogxK
U2 - 10.1034/j.1399-0012.2002.02034.x
DO - 10.1034/j.1399-0012.2002.02034.x
M3 - Article
C2 - 12225437
AN - SCOPUS:0036786197
VL - 16
SP - 383
EP - 386
JO - Clinical Transplantation
JF - Clinical Transplantation
SN - 0902-0063
IS - 5
ER -