Abstract
Many inherited skin conditions are associated with underlying malignancies. The astute clinician will be able to recognize many of these cutaneous findings. The identification of these genetic syndromes with cutaneous findings, or genodermatoses, may allow early recognition of internal malignancies and the extension of these patients' life expectancy. Several of these syndromes have established screening and treatment protocols, which should be utilized in the care of affected patients. This article succinctly reviews the dermatologic, clinical, and laboratory findings associated with genodermatoses that have associated internal malignancies. Appropriate treatment and screening recommendations are explored.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 606-642 |
| Number of pages | 37 |
| Journal | Dermatologic Therapy |
| Volume | 23 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 2010 |
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Keywords
- cutaneous
- genodermatoses
- malignancy
- paraneoplastic
- syndromes
ASJC Scopus subject areas
- Dermatology
Cite this
Inherited syndromes. / Reyes, Melissa A.; Eisen, Daniel B.
In: Dermatologic Therapy, Vol. 23, No. 6, 11.2010, p. 606-642.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Inherited syndromes
AU - Reyes, Melissa A.
AU - Eisen, Daniel B
PY - 2010/11
Y1 - 2010/11
N2 - Many inherited skin conditions are associated with underlying malignancies. The astute clinician will be able to recognize many of these cutaneous findings. The identification of these genetic syndromes with cutaneous findings, or genodermatoses, may allow early recognition of internal malignancies and the extension of these patients' life expectancy. Several of these syndromes have established screening and treatment protocols, which should be utilized in the care of affected patients. This article succinctly reviews the dermatologic, clinical, and laboratory findings associated with genodermatoses that have associated internal malignancies. Appropriate treatment and screening recommendations are explored.
AB - Many inherited skin conditions are associated with underlying malignancies. The astute clinician will be able to recognize many of these cutaneous findings. The identification of these genetic syndromes with cutaneous findings, or genodermatoses, may allow early recognition of internal malignancies and the extension of these patients' life expectancy. Several of these syndromes have established screening and treatment protocols, which should be utilized in the care of affected patients. This article succinctly reviews the dermatologic, clinical, and laboratory findings associated with genodermatoses that have associated internal malignancies. Appropriate treatment and screening recommendations are explored.
KW - cutaneous
KW - genodermatoses
KW - malignancy
KW - paraneoplastic
KW - syndromes
UR - http://www.scopus.com/inward/record.url?scp=78449292671&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78449292671&partnerID=8YFLogxK
U2 - 10.1111/j.1529-8019.2010.01368.x
DO - 10.1111/j.1529-8019.2010.01368.x
M3 - Article
VL - 23
SP - 606
EP - 642
JO - Dermatologic Therapy
JF - Dermatologic Therapy
SN - 1396-0296
IS - 6
ER -