Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide

Lisa K. Kelly, Nicolas F M Porta, Denise M. Goodman, Christopher L. Carroll, Robin H Steinhorn

Research output: Contribution to journalArticle

125 Scopus citations


We report the use of inhaled prostacyclin (PGI2) in 4 neonates with persistent pulmonary hypertension and hypoxemia refractory to inhaled nitric oxide. Oxygenation rapidly improved after inhalation of PGI2 in all infants. The condition of one infant subsequently deteriorated, and alveolar capillary dysplasia was found at autopsy. The surviving infants were discharged with normal oxygen saturations in room air.

Original languageEnglish (US)
Pages (from-to)830-832
Number of pages3
JournalJournal of Pediatrics
Issue number6
StatePublished - Dec 1 2002
Externally publishedYes


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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