Infrared multiphoton dissociation of alkali metal-coordinated oligosaccharides

Yongming Xie, Carlito B Lebrilla

Research output: Contribution to journalArticle

85 Scopus citations

Abstract

Infrared multiphoton dissociation (IRMPD) of alkali metal-coordinated oligosaccharides was obtained in a Fourier transform mass spectrometer. Fragmentation of the oligosaccharides was observed for Li+- and Na+coordinated species. For larger alkali metal ions (K+, Rb+, and Cs+), the major products were the alkali metal ions. IRMPD experiments were performed on milk oligosaccharides, and the dissociation thresholds were determined. The threshold values were found to differ for the isomers. It is suggested that the threshold may be useful for differentiating isomeric compounds. Additionally, oligosaccharide alditols from biological samples were analyzed. Comparison of the collision-induced dissociation (CID) and IRMPD spectra of oligosaccharide al000ditols revealed that IRMPD could be used as a complementary method to obtain structural information.

Original languageEnglish (US)
Pages (from-to)1590-1598
Number of pages9
JournalAnalytical Chemistry
Volume75
Issue number7
DOIs
StatePublished - Apr 1 2003

ASJC Scopus subject areas

  • Analytical Chemistry

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