Influence of SLA haplotype on ovulation rate and litter size in miniature pigs

Alan J Conley, Y. C. Jung, N. K. Schwartz, C. M. Warner, M. F. Rothschild, S. P. Ford

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Systemic blood was collected from and surgery performed on sows of 3 strains of miniataure swine bred for specific SLA (swine MHC) haplotypes (a, c and d) from Day 2 to Day 6 after mating (first day of mating = Day 0). Ovulation rate was determined by counting corpora lutea and embryos were flushed from the uterus. Progesterone, oestradiol-17β and oestrone were quantitated in blood plasma and uterine flushings by RIA. SLA(d/d) females had higher ovulation rate than SLA(a/a) or SLA(c/c) females (11.50 ± 0.87 vs 9.11 ± 0.68 and 8.17 ± 0.83, respectively; P < 0.01). Oestrone was higher than oestradiol-17β in systemic plasma (56.5 ± 6.4 vs 33.0 ± 4.7 pg/ml, P < 0.01) while oestradiol-17β was higher than oestrone in uterine flushings (19.8 ± 1.4 vs 14.9 ± 1.5 pg/horn, P < 0.10). Systemic progesterone concentration was correlated with day after mating (r = 0.93, P < 0.01). There was no effect of haplotype on any of the hormone concentrations measured. Litter size was analysed from 99 matings amongst SLA(a/a), SLA(a/c), SLA(a/d), SLA(d/c) sires and dams. Litter size from -/d and d/d sows or from d/d boars were larger (P < 0.05) than for all other matings. Although ovulation rate was higher in SLA(d/d) sows, the significant effect of sire SLA genotype on litter size suggests an additional effect of the d haplotype on embryonic survival.

Original languageEnglish (US)
Pages (from-to)595-601
Number of pages7
JournalJournal of Reproduction and Fertility
Volume82
Issue number2
StatePublished - 1988
Externally publishedYes

Fingerprint

Litter Size
Estrone
Ovulation
Haplotypes
Estradiol
Swine
Progesterone
Dilatation and Curettage
Corpus Luteum
Horns
Uterus
Embryonic Structures
Genotype
Hormones

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Physiology
  • Embryology
  • Obstetrics and Gynecology

Cite this

Conley, A. J., Jung, Y. C., Schwartz, N. K., Warner, C. M., Rothschild, M. F., & Ford, S. P. (1988). Influence of SLA haplotype on ovulation rate and litter size in miniature pigs. Journal of Reproduction and Fertility, 82(2), 595-601.

Influence of SLA haplotype on ovulation rate and litter size in miniature pigs. / Conley, Alan J; Jung, Y. C.; Schwartz, N. K.; Warner, C. M.; Rothschild, M. F.; Ford, S. P.

In: Journal of Reproduction and Fertility, Vol. 82, No. 2, 1988, p. 595-601.

Research output: Contribution to journalArticle

Conley, AJ, Jung, YC, Schwartz, NK, Warner, CM, Rothschild, MF & Ford, SP 1988, 'Influence of SLA haplotype on ovulation rate and litter size in miniature pigs', Journal of Reproduction and Fertility, vol. 82, no. 2, pp. 595-601.
Conley, Alan J ; Jung, Y. C. ; Schwartz, N. K. ; Warner, C. M. ; Rothschild, M. F. ; Ford, S. P. / Influence of SLA haplotype on ovulation rate and litter size in miniature pigs. In: Journal of Reproduction and Fertility. 1988 ; Vol. 82, No. 2. pp. 595-601.
@article{2def0a01b2ad4c749a97745ed42eaddf,
title = "Influence of SLA haplotype on ovulation rate and litter size in miniature pigs",
abstract = "Systemic blood was collected from and surgery performed on sows of 3 strains of miniataure swine bred for specific SLA (swine MHC) haplotypes (a, c and d) from Day 2 to Day 6 after mating (first day of mating = Day 0). Ovulation rate was determined by counting corpora lutea and embryos were flushed from the uterus. Progesterone, oestradiol-17β and oestrone were quantitated in blood plasma and uterine flushings by RIA. SLA(d/d) females had higher ovulation rate than SLA(a/a) or SLA(c/c) females (11.50 ± 0.87 vs 9.11 ± 0.68 and 8.17 ± 0.83, respectively; P < 0.01). Oestrone was higher than oestradiol-17β in systemic plasma (56.5 ± 6.4 vs 33.0 ± 4.7 pg/ml, P < 0.01) while oestradiol-17β was higher than oestrone in uterine flushings (19.8 ± 1.4 vs 14.9 ± 1.5 pg/horn, P < 0.10). Systemic progesterone concentration was correlated with day after mating (r = 0.93, P < 0.01). There was no effect of haplotype on any of the hormone concentrations measured. Litter size was analysed from 99 matings amongst SLA(a/a), SLA(a/c), SLA(a/d), SLA(d/c) sires and dams. Litter size from -/d and d/d sows or from d/d boars were larger (P < 0.05) than for all other matings. Although ovulation rate was higher in SLA(d/d) sows, the significant effect of sire SLA genotype on litter size suggests an additional effect of the d haplotype on embryonic survival.",
author = "Conley, {Alan J} and Jung, {Y. C.} and Schwartz, {N. K.} and Warner, {C. M.} and Rothschild, {M. F.} and Ford, {S. P.}",
year = "1988",
language = "English (US)",
volume = "82",
pages = "595--601",
journal = "Journal of Reproduction and Fertility",
issn = "0022-4251",
publisher = "Society for Reproduction and Fertility",
number = "2",

}

TY - JOUR

T1 - Influence of SLA haplotype on ovulation rate and litter size in miniature pigs

AU - Conley, Alan J

AU - Jung, Y. C.

AU - Schwartz, N. K.

AU - Warner, C. M.

AU - Rothschild, M. F.

AU - Ford, S. P.

PY - 1988

Y1 - 1988

N2 - Systemic blood was collected from and surgery performed on sows of 3 strains of miniataure swine bred for specific SLA (swine MHC) haplotypes (a, c and d) from Day 2 to Day 6 after mating (first day of mating = Day 0). Ovulation rate was determined by counting corpora lutea and embryos were flushed from the uterus. Progesterone, oestradiol-17β and oestrone were quantitated in blood plasma and uterine flushings by RIA. SLA(d/d) females had higher ovulation rate than SLA(a/a) or SLA(c/c) females (11.50 ± 0.87 vs 9.11 ± 0.68 and 8.17 ± 0.83, respectively; P < 0.01). Oestrone was higher than oestradiol-17β in systemic plasma (56.5 ± 6.4 vs 33.0 ± 4.7 pg/ml, P < 0.01) while oestradiol-17β was higher than oestrone in uterine flushings (19.8 ± 1.4 vs 14.9 ± 1.5 pg/horn, P < 0.10). Systemic progesterone concentration was correlated with day after mating (r = 0.93, P < 0.01). There was no effect of haplotype on any of the hormone concentrations measured. Litter size was analysed from 99 matings amongst SLA(a/a), SLA(a/c), SLA(a/d), SLA(d/c) sires and dams. Litter size from -/d and d/d sows or from d/d boars were larger (P < 0.05) than for all other matings. Although ovulation rate was higher in SLA(d/d) sows, the significant effect of sire SLA genotype on litter size suggests an additional effect of the d haplotype on embryonic survival.

AB - Systemic blood was collected from and surgery performed on sows of 3 strains of miniataure swine bred for specific SLA (swine MHC) haplotypes (a, c and d) from Day 2 to Day 6 after mating (first day of mating = Day 0). Ovulation rate was determined by counting corpora lutea and embryos were flushed from the uterus. Progesterone, oestradiol-17β and oestrone were quantitated in blood plasma and uterine flushings by RIA. SLA(d/d) females had higher ovulation rate than SLA(a/a) or SLA(c/c) females (11.50 ± 0.87 vs 9.11 ± 0.68 and 8.17 ± 0.83, respectively; P < 0.01). Oestrone was higher than oestradiol-17β in systemic plasma (56.5 ± 6.4 vs 33.0 ± 4.7 pg/ml, P < 0.01) while oestradiol-17β was higher than oestrone in uterine flushings (19.8 ± 1.4 vs 14.9 ± 1.5 pg/horn, P < 0.10). Systemic progesterone concentration was correlated with day after mating (r = 0.93, P < 0.01). There was no effect of haplotype on any of the hormone concentrations measured. Litter size was analysed from 99 matings amongst SLA(a/a), SLA(a/c), SLA(a/d), SLA(d/c) sires and dams. Litter size from -/d and d/d sows or from d/d boars were larger (P < 0.05) than for all other matings. Although ovulation rate was higher in SLA(d/d) sows, the significant effect of sire SLA genotype on litter size suggests an additional effect of the d haplotype on embryonic survival.

UR - http://www.scopus.com/inward/record.url?scp=0023828781&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023828781&partnerID=8YFLogxK

M3 - Article

C2 - 3361494

AN - SCOPUS:0023828781

VL - 82

SP - 595

EP - 601

JO - Journal of Reproduction and Fertility

JF - Journal of Reproduction and Fertility

SN - 0022-4251

IS - 2

ER -