Influence of patient, physician, and hospital characteristics on the receipt of guideline-concordant care for inflammatory breast cancer

Ryan A. Denu, John M. Hampton, Adam Currey, Roger T. Anderson, Rosemary D Cress, Steven T. Fleming, Joseph Lipscomb, Susan A. Sabatino, Xiao Cheng Wu, J. Frank Wilson, Amy Trentham-Dietz

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Purpose: Inflammatory breast cancer (IBC) is an aggressive subtype of breast cancer for which treatments vary, so we sought to identify factors that affect the receipt of guideline-concordant care. Methods: Patients diagnosed with IBC in 2004 were identified from the Breast and Prostate Cancer Data Quality and Patterns of Care Study, containing information from cancer registries in seven states. Variation in guideline-concordant care for IBC, based on National Comprehensive Cancer Network (NCCN) guidelines, was assessed according to patient, physician, and hospital characteristics. Results: Of the 107 IBC patients in the study without distant metastasis at the time of diagnosis, only 25.8% received treatment concordant with guidelines. Predictors of non-concordance included patient age (≥70 years), non-white race, normal body mass index (BMI 18.5-25 kg/m2), patients with physicians graduating from medical school >15 years prior, and smaller hospital size (<200 beds). IBC patients survived longer if they received guideline-concordant treatment based on either 2003 (p = 0.06) or 2013 (p = 0.06) NCCN guidelines. Conclusions: Targeting factors associated with receipt of care that is not guideline-concordant may reduce survival disparities in IBC patients. Prompt referral for neoadjuvant chemotherapy and post-operative radiation therapy is also crucial.

Original languageEnglish (US)
Pages (from-to)7-14
Number of pages8
JournalCancer Epidemiology
Volume40
DOIs
StatePublished - Feb 1 2016

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Keywords

  • Breast cancer
  • Epidemiology
  • Guideline
  • Healthcare disparities
  • Inflammatory breast cancer

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Epidemiology

Cite this

Denu, R. A., Hampton, J. M., Currey, A., Anderson, R. T., Cress, R. D., Fleming, S. T., Lipscomb, J., Sabatino, S. A., Wu, X. C., Wilson, J. F., & Trentham-Dietz, A. (2016). Influence of patient, physician, and hospital characteristics on the receipt of guideline-concordant care for inflammatory breast cancer. Cancer Epidemiology, 40, 7-14. https://doi.org/10.1016/j.canep.2015.11.003