Influence of cross-correlation between dipolar and chemical shift anisotropy relaxation mechanisms upon the transverse relaxation rates of 15N in macromolecules

Jonathan Boyd, Ulrich Hommel, Viswanathan V Krishnan

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

Heteronuclear multiple-quantum coherence relaxation rate are calculated for the individual transitions of the S spin in an AIS nuclear spin system assuming that the heteronucleus (S spin) has relaxation contributions from both intramolecular dipole-dipole and chemical shift anisotropy relaxation. The individual multiplet components of the heteronuclear zero- and double-quantum coherences are shown to have different transverse relaxation rates. The cross-correlation between the two relaxation mechanisms is shown to be the dominant cause of the calculated differential line broadening. Experimental data are presented using as an example a uniformly 15N labelled sample of human epidermal growth factor.

Original languageEnglish (US)
Pages (from-to)317-324
Number of pages8
JournalChemical Physics Letters
Volume187
Issue number3
DOIs
StatePublished - Dec 6 1991
Externally publishedYes

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Condensed Matter Physics
  • Atomic and Molecular Physics, and Optics
  • Surfaces and Interfaces

Fingerprint Dive into the research topics of 'Influence of cross-correlation between dipolar and chemical shift anisotropy relaxation mechanisms upon the transverse relaxation rates of <sup>15</sup>N in macromolecules'. Together they form a unique fingerprint.

  • Cite this