Infestation in the dog by the paralysis tick, Ixodes holocyclus. 5. Treatment.

Jan Ilkiw, D. M. Turner

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


In this study the value of drugs administered with hyperimmune serum in the treatment of advanced disease produced by Ixodes holocyclus was compared under controlled conditions. All control dogs died rapidly whereas one dog survived and 3 dogs died after receiving hyperimmune serum alone. When promethazine hydrochloride was administered with hyperimmune serum 2 dogs recovered rapidly while the remaining 2 died. Administration of dexamethasone and hyperimmune serum allowed 3 dogs to survive while administration of phenoxybenzamine hydrochloride in conjunction with hyperimmune serum allowed rapid recovery of all 4 dogs. Phenoxybenzamine hydrochloride, an alpha-adrenergic blocking drug, was chosen because of its potential to attenuate the arterial hypertension previously reported (Ilkiw et al 1988). The survival of all dogs together with the rapid return to normality indicated that this drug was beneficial in the treatment of dogs with advanced signs of tick paralysis.

Original languageEnglish (US)
Pages (from-to)236-238
Number of pages3
JournalAustralian Veterinary Journal
Issue number8
StatePublished - Aug 1988
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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