Infectious keratitis after astigmatic keratotomy in penetrating keratoplasty: Review of three cases

Sean D. Adrean, Rochelle Cochrane, Charles D. Reilly, Mark J Mannis

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: To present 3 cases in 2 patients of infectious keratitis of the astigmatic keratotomy (AK) site in patients who had previous penetrating keratoplasty. Methods: History, clinical examination, chart review, cultures, and laboratory results were obtained from 2 patients with infectious keratitis within the donor stroma of their graft after an AK was performed. Results: One patient had an early infiltrate of the AK site that was culture negative. This cleared with fortified antibiotics, and the patient had a final visual acuity of 20/30-2. The second patient developed 2 late infections, the first with coagulase negative Staphylococcus and the second infection with Pseudomonas aeruginosa. Both of these infections cleared with fortified antibiotics, and the final visual acuity was 20/25. Neither patient developed a rejection episode from the infections, and both grafts survived. Conclusions: We report a series of 3 cases of infectious keratitis in 2 patients after AKs in corneal grafts. This, to the best of our knowledge, has not been previously reported. Patients who suffer infectious keratitis after AK in corneal grafts may have good visual outcomes if managed with appropriate antibiotic regimens and closely followed.

Original languageEnglish (US)
Pages (from-to)626-628
Number of pages3
JournalCornea
Volume24
Issue number5
DOIs
StatePublished - Jul 2005

Fingerprint

Penetrating Keratoplasty
Keratitis
Transplants
Anti-Bacterial Agents
Infection
Visual Acuity
Coagulase
Staphylococcus
Pseudomonas aeruginosa
History
Tissue Donors

Keywords

  • Astigmatic keratotomy
  • Infectious keratitis
  • Penetrating keratoplasty

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Infectious keratitis after astigmatic keratotomy in penetrating keratoplasty : Review of three cases. / Adrean, Sean D.; Cochrane, Rochelle; Reilly, Charles D.; Mannis, Mark J.

In: Cornea, Vol. 24, No. 5, 07.2005, p. 626-628.

Research output: Contribution to journalArticle

Adrean, Sean D. ; Cochrane, Rochelle ; Reilly, Charles D. ; Mannis, Mark J. / Infectious keratitis after astigmatic keratotomy in penetrating keratoplasty : Review of three cases. In: Cornea. 2005 ; Vol. 24, No. 5. pp. 626-628.
@article{5c9d6144fbd0461fb3f134f87cfc9392,
title = "Infectious keratitis after astigmatic keratotomy in penetrating keratoplasty: Review of three cases",
abstract = "Purpose: To present 3 cases in 2 patients of infectious keratitis of the astigmatic keratotomy (AK) site in patients who had previous penetrating keratoplasty. Methods: History, clinical examination, chart review, cultures, and laboratory results were obtained from 2 patients with infectious keratitis within the donor stroma of their graft after an AK was performed. Results: One patient had an early infiltrate of the AK site that was culture negative. This cleared with fortified antibiotics, and the patient had a final visual acuity of 20/30-2. The second patient developed 2 late infections, the first with coagulase negative Staphylococcus and the second infection with Pseudomonas aeruginosa. Both of these infections cleared with fortified antibiotics, and the final visual acuity was 20/25. Neither patient developed a rejection episode from the infections, and both grafts survived. Conclusions: We report a series of 3 cases of infectious keratitis in 2 patients after AKs in corneal grafts. This, to the best of our knowledge, has not been previously reported. Patients who suffer infectious keratitis after AK in corneal grafts may have good visual outcomes if managed with appropriate antibiotic regimens and closely followed.",
keywords = "Astigmatic keratotomy, Infectious keratitis, Penetrating keratoplasty",
author = "Adrean, {Sean D.} and Rochelle Cochrane and Reilly, {Charles D.} and Mannis, {Mark J}",
year = "2005",
month = "7",
doi = "10.1097/01.ico.0000151552.70982.6e",
language = "English (US)",
volume = "24",
pages = "626--628",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Infectious keratitis after astigmatic keratotomy in penetrating keratoplasty

T2 - Review of three cases

AU - Adrean, Sean D.

AU - Cochrane, Rochelle

AU - Reilly, Charles D.

AU - Mannis, Mark J

PY - 2005/7

Y1 - 2005/7

N2 - Purpose: To present 3 cases in 2 patients of infectious keratitis of the astigmatic keratotomy (AK) site in patients who had previous penetrating keratoplasty. Methods: History, clinical examination, chart review, cultures, and laboratory results were obtained from 2 patients with infectious keratitis within the donor stroma of their graft after an AK was performed. Results: One patient had an early infiltrate of the AK site that was culture negative. This cleared with fortified antibiotics, and the patient had a final visual acuity of 20/30-2. The second patient developed 2 late infections, the first with coagulase negative Staphylococcus and the second infection with Pseudomonas aeruginosa. Both of these infections cleared with fortified antibiotics, and the final visual acuity was 20/25. Neither patient developed a rejection episode from the infections, and both grafts survived. Conclusions: We report a series of 3 cases of infectious keratitis in 2 patients after AKs in corneal grafts. This, to the best of our knowledge, has not been previously reported. Patients who suffer infectious keratitis after AK in corneal grafts may have good visual outcomes if managed with appropriate antibiotic regimens and closely followed.

AB - Purpose: To present 3 cases in 2 patients of infectious keratitis of the astigmatic keratotomy (AK) site in patients who had previous penetrating keratoplasty. Methods: History, clinical examination, chart review, cultures, and laboratory results were obtained from 2 patients with infectious keratitis within the donor stroma of their graft after an AK was performed. Results: One patient had an early infiltrate of the AK site that was culture negative. This cleared with fortified antibiotics, and the patient had a final visual acuity of 20/30-2. The second patient developed 2 late infections, the first with coagulase negative Staphylococcus and the second infection with Pseudomonas aeruginosa. Both of these infections cleared with fortified antibiotics, and the final visual acuity was 20/25. Neither patient developed a rejection episode from the infections, and both grafts survived. Conclusions: We report a series of 3 cases of infectious keratitis in 2 patients after AKs in corneal grafts. This, to the best of our knowledge, has not been previously reported. Patients who suffer infectious keratitis after AK in corneal grafts may have good visual outcomes if managed with appropriate antibiotic regimens and closely followed.

KW - Astigmatic keratotomy

KW - Infectious keratitis

KW - Penetrating keratoplasty

UR - http://www.scopus.com/inward/record.url?scp=21244486745&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21244486745&partnerID=8YFLogxK

U2 - 10.1097/01.ico.0000151552.70982.6e

DO - 10.1097/01.ico.0000151552.70982.6e

M3 - Article

C2 - 15968174

AN - SCOPUS:21244486745

VL - 24

SP - 626

EP - 628

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 5

ER -